3-ALLYLOXYPROPIONIC ACID

Base Information

• Chemical Name: 3-ALLYLOXYPROPIONIC ACID
• CAS No.: 22577-15-7
• Molecular Formula: C6H10O3
• Molecular Weight: 130.14
• Hs Code.: 2918999090
• Mol file: 22577-15-7.mol

Synonyms:Propanoicacid, 3-(2-propenyloxy)- (9CI);Propionic acid, 3-(allyloxy)- (6CI,7CI,8CI);3-(2-Propenyloxy)propanoic acid;3-Allyloxypropionic acid;

Chemical Property of 3-ALLYLOXYPROPIONIC ACID

Chemical Property:

• Refractive Index: 1.4400-1.4430
• Boiling Point: 225.5 °C at 760 mmHg
• PKA: 4.36±0.10(Predicted)
• Flash Point: 91.7 °C
• PSA: 46.53000
• Density: 1.052 g/cm³
• LogP: 0.66370
• Storage Temp.: Refrigerator

Purity/Quality:

98%,99%, ^*data from raw suppliers

3-Allyloxypropionic Acid ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 3-Allyloxypropionic Acid is a useful intermediate for plasticizers and other chemical industry.

Technology Process of 3-ALLYLOXYPROPIONIC ACID

There total 8 articles about 3-ALLYLOXYPROPIONIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

tert-butyl 3-(2-propenoxy)propanoate → 3-(allyloxy)propionic acid (22577-15-7)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 5h; Inert atmosphere;

DOI:10.1002/chem.201402684

Reference yield: 63.0%

3-allyloxy-propionitrile (3088-44-6) → 3-(allyloxy)propionic acid (22577-15-7)

Guidance literature:

With sodium peroxide; dihydrogen peroxide; In methanol; for 46h;

DOI:10.1080/00397919308009812

Reference yield:

1-(allyloxy)-2-(methoxycarbonyl)ethane (93639-67-9) → 3-(allyloxy)propionic acid (22577-15-7)

Guidance literature:

With potassium hydroxide; In ethanol; at 25 ℃; for 48h;

DOI:10.1039/c5dt03808a

upstream raw materials:

3-allyloxy-propionitrile

β-Propiolactone

allyl alcohol

acrylonitrile

Downstream raw materials:

Se-Phenyl 4-Oxaselenohept-6-enoate

3-ethyl tetrahydrofuran

allyl propyl ether

(S)-2-[4-(3-Allyloxy-propionylamino)-benzoylamino]-pentanedioic acid di-tert-butyl ester

Refernces

• 1、 Verma, Ajay,Jana, Sadhan,Prasad, Ch. Durga,Yadav, Abhimanyu,Kumar, Sangit. "Organoselenium and DMAP co-catalysis: Regioselective synthesis of medium-sized halolactones and bromooxepanes from unactivated alkenes". supporting information. p. 4179 - 4182. Retrieved 2016/03/19.
• 2、 Belmessieri, Dorine,De La Houpliere, Alix,Calder, Ewen D. D.,Taylor, James E.,Smith, Andrew D.. "Stereodivergent organocatalytic intramolecular michael addition/ lactonization for the asymmetric synthesis of substituted dihydrobenzofurans and tetrahydrofurans". supporting information. p. 9762 - 9769. Retrieved 2014/08/18.