methyl (E)-2-bromo-2-penylethenyl sulfone

Base Information

• Chemical Name: methyl (E)-2-bromo-2-penylethenyl sulfone
• CAS No.: 52920-44-2
• Molecular Formula: C₉H₉BrO₂S
• Molecular Weight: 261.139
• Mol file: 52920-44-2.mol

Synonyms:methyl (E)-2-bromo-2-penylethenyl sulfone

Chemical Property of methyl (E)-2-bromo-2-penylethenyl sulfone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl (E)-2-bromo-2-penylethenyl sulfone

There total 3 articles about methyl (E)-2-bromo-2-penylethenyl sulfone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

methanesulfonyl bromide (41138-92-5) + phenylacetylene (536-74-3) → methyl (E)-2-bromo-2-penylethenyl sulfone (52920-44-2)

Guidance literature:

With triethyl borane; oxygen; In acetonitrile; at 20 ℃; for 12h; stereoselective reaction;

DOI:10.1071/CH12499

Reference yield: 74.0%

methanesulfonic acid sodium salt (2386-57-4) + phenylacetylene (536-74-3) → methyl (E)-2-bromo-2-penylethenyl sulfone (52920-44-2)

Guidance literature:

With [2,2]bipyridinyl; copper(l) iodide; potassium bromide; In acetic acid; at 100 ℃; for 18h; stereoselective reaction;

DOI:10.1055/s-0030-1260544

Reference yield:

→ methyl (E)-2-bromo-2-penylethenyl sulfone (52920-44-2)

Guidance literature:

Phenylacetylen, Methansulfonylbromid;

DOI:10.1021/jo00940a014

upstream raw materials:

methanesulfonyl bromide

phenylacetylene

methanesulfonic acid sodium salt

Downstream raw materials:

(2,2-dimethoxy-2-phenylethyl) methyl sulfone

2-[2-(methylsulfonyl)-1-phenylethylidene]malononitrile

Refernces

• 1、 Gilmore, Kerry,Gold, Brian,Clark, Ronald J.,Alabugin, Igor V.. "Convenient ambient temperature generation of sulfonyl radicals". . p. 336 - 340. Retrieved 2013/05/08.
• 2、 Vasin,Bolusheva,Razin. "Condensation products of mono-and dibromo-substituted methyl vinyl sulfones with CH-acids enolates". experimental part. p. 419 - 429. Retrieved 2009/04/11.