(E)-pyrrole-2-carboxaldehyde oxime

Base Information

• Chemical Name: (E)-pyrrole-2-carboxaldehyde oxime
• CAS No.: 960622-17-7
• Molecular Formula: C₅H₆N₂O
• Molecular Weight: 110.115
• Mol file: 960622-17-7.mol

Synonyms:(E)-pyrrole-2-carboxaldehyde oxime

Chemical Property of (E)-pyrrole-2-carboxaldehyde oxime

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

(E)-1H-Pyrrole-2-carbaldehydeoxime 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-pyrrole-2-carboxaldehyde oxime

There total 5 articles about (E)-pyrrole-2-carboxaldehyde oxime which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

2-pyrrole aldehyde (1003-29-8,254729-95-8) → (E)-pyrrole-2-carboxaldehyde oxime (960622-17-7)

Guidance literature:

With hydroxylamine hydrochloride; In ethanol; water; for 0.166667h; Microwave irradiation;

DOI:10.1590/S0103-50532012000700004

Reference yield: 58.0%

2-pyrrole aldehyde (1003-29-8,254729-95-8) + carbonic acid dimethyl ester (616-38-6) → 1-acetyl-pyrrole-2-carbonitrile (18023-27-3) + (E)-pyrrole-2-carboxaldehyde oxime (960622-17-7)

Guidance literature:

With hydroxylamine hydrochloride; triethylamine; In acetonitrile; Heating;

DOI:10.1016/S0040-4039(98)00654-6

Reference yield: 33.0%

2-pyrrole aldehyde (1003-29-8,254729-95-8) → 1-acetyl-pyrrole-2-carbonitrile (18023-27-3) + (E)-pyrrole-2-carboxaldehyde oxime (960622-17-7)

Guidance literature:

With hydroxylamine hydrochloride; acetic anhydride; triethylamine; In acetonitrile; Heating;

DOI:10.1016/S0040-4039(98)00654-6

upstream raw materials:

2-pyrrole aldehyde

carbonic acid dimethyl ester

Downstream raw materials:

2,2'-bipyrrole

(1H-pyrrol-2-yl)methylamine

2-amino-methylpyrrolidine

2-pyrrole aldehyde

Refernces

• 1、 Wang, Eng-Chi,Lin, Gow-Juin. "A new one pot method for the conversion of aldehydes into nitriles using hydroxyamine and phthalic anhydride". . p. 4047 - 4050. Retrieved 2007/10/03.