6,7-Dimethoxy-4-piperazin-1-yl-quinazoline

Base Information

• Chemical Name: 6,7-Dimethoxy-4-piperazin-1-yl-quinazoline
• CAS No.: 21584-72-5
• Molecular Formula: C14H18 N4 O2
• Molecular Weight: 274.32
• Hs Code.: 2933990090
• European Community (EC) Number: 674-678-7
• DSSTox Substance ID: DTXSID10374345
• Wikidata: Q82162896
• Mol file: 21584-72-5.mol

Synonyms:6,7-dimethoxy-4-piperazin-1-yl-quinazoline;21584-72-5;6,7-dimethoxy-4-piperazin-1-ylquinazoline;6,7-dimethoxy-4-(piperazin-1-yl)quinazoline;6,7-dimethoxy-4-(1-piperazinyl)quinazoline;SCHEMBL2389420;AMY1694;DTXSID10374345;HGQPTOFRZXUHHS-UHFFFAOYSA-N;MFCD04973792;AKOS002365161;6,7-dimethoxy-4-piperazinylquinazoline;DS-0302;CS-0320685;FT-0762809;4-(1-piperazinyl)-6,7-dimethoxy quinazoline;4-(I-piperazinyl)-6,7-dimethoxy quinazoline;A815502

Chemical Property of 6,7-Dimethoxy-4-piperazin-1-yl-quinazoline

Chemical Property:

• Vapor Pressure: 1E-08mmHg at 25°C
• Refractive Index: 1.597
• Boiling Point: 462.2°C at 760 mmHg
• PKA: 9.48±0.70(Predicted)
• Flash Point: 233.4°C
• PSA: 59.51000
• Density: 1.212g/cm³
• LogP: 1.45040
• Storage Temp.: 2-8°C
• XLogP3: 1.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 3
• Exact Mass: 274.14297583
• Heavy Atom Count: 20
• Complexity: 312

Purity/Quality:

98%min ^*data from raw suppliers

6,7-Dimethoxy-4-piperazin-1-yl-quinazoline 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=C(C=C2C(=C1)C(=NC=N2)N3CCNCC3)OC

Technology Process of 6,7-Dimethoxy-4-piperazin-1-yl-quinazoline

There total 5 articles about 6,7-Dimethoxy-4-piperazin-1-yl-quinazoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

→ 6,7-dimethoxy-4-(1-piperazinyl)quinazoline (21584-72-5) + 4-(6,7-Dimethoxy-4-quinazolinyl)-N-(4-isopropylbenzyl)-1-piperazinethiocarboxamide

Guidance literature:

Reference yield: 63.0%

→ 4-(6,7-Dimethoxy-4-quinazolinyl)-N-(3-isopropylphenyl)-1-piperazinecarboxamide + 6,7-dimethoxy-4-(1-piperazinyl)quinazoline (21584-72-5)

Guidance literature:

Reference yield: 44.0%

→ 6,7-dimethoxy-4-(1-piperazinyl)quinazoline (21584-72-5) + 4-(6,7-Dimethoxy-4-quinazolinyl)-N-phenyl-1-piperazinecarboxamide

Guidance literature:

Downstream raw materials:

KN 1022

Refernces