2,4-DIMETHYL-3-FLUORO-BROMOBENZENE

Base Information

• Chemical Name: 2,4-DIMETHYL-3-FLUORO-BROMOBENZENE
• CAS No.: 26584-26-9
• Molecular Formula: C₈H₈BrF
• Molecular Weight: 203.054
• Hs Code.: 2903999090
• Mol file: 26584-26-9.mol

Synonyms:m-Xylene,4-bromo-2-fluoro- (8CI)

Chemical Property of 2,4-DIMETHYL-3-FLUORO-BROMOBENZENE

Chemical Property:

• Vapor Pressure: 0.349mmHg at 25°C
• Refractive Index: 1.524
• Boiling Point: 206°Cat760mmHg
• Flash Point: 81°C
• PSA: 0.00000
• Density: 1.426g/cm³
• LogP: 3.20500

Purity/Quality:

99%, ^*data from raw suppliers

2,4-Dimethyl-3-fluorobromobenzene 98% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,4-DIMETHYL-3-FLUORO-BROMOBENZENE

There total 1 articles about 2,4-DIMETHYL-3-FLUORO-BROMOBENZENE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-bromo-2,6-dimethyl-aniline (53874-26-3) → 4-Brom-2-fluor-1.3-dimethylbenzol (26584-26-9)

Guidance literature:

Multistep reaction; (i) NaNO₂, aq. H₂SO₄, (ii) HBF₄;

DOI:10.1021/jo00836a010

Reference yield:

4-Brom-2-fluor-1.3-dimethylbenzol (26584-26-9) → 3-Fluoro-1,2,4-trimethylbenzene (26630-72-8)

Guidance literature:

Multi-step reaction with 5 steps

1: (i) Mg, THF, (ii) /BRN= 1900390/

2: (i) SOCl₂, (ii) /BRN= 1098229/

3: LiAlH₄ / diethyl ether

4: SOCl₂

5: LiAlH₄ / tetrahydrofuran

With lithium aluminium tetrahydride; thionyl chloride; In tetrahydrofuran; diethyl ether;

DOI:10.1021/jo00836a010

Reference yield:

4-Brom-2-fluor-1.3-dimethylbenzol (26584-26-9) → 6-Brom-3-fluor-1.2.4-trimethylbenzol (26583-84-6)

Guidance literature:

Multi-step reaction with 6 steps

1: (i) Mg, THF, (ii) /BRN= 1900390/

2: (i) SOCl₂, (ii) /BRN= 1098229/

3: LiAlH₄ / diethyl ether

4: SOCl₂

5: LiAlH₄ / tetrahydrofuran

6: Br₂ / CHCl₃

With lithium aluminium tetrahydride; thionyl chloride; bromine; In tetrahydrofuran; diethyl ether; chloroform;

DOI:10.1021/jo00836a010

upstream raw materials:

3-bromo-2,6-dimethyl-aniline

Downstream raw materials:

3-fluoro-2,4-dimethylbenzoic acid

3-Fluoro-1,2,4-trimethylbenzene

6-Brom-3-fluor-1.2.4-trimethylbenzol

3-Fluor-2.4-dimethylbenzylchlorid