C₁₀H₁₃N₃O₃

Base Information

• Chemical Name: C₁₀H₁₃N₃O₃
• CAS No.: 129521-46-6
• Molecular Formula: C₁₀H₁₃N₃O₃
• Molecular Weight: 223.232
• Mol file: 129521-46-6.mol

Synonyms:C₁₀H₁₃N₃O₃

Chemical Property of C₁₀H₁₃N₃O₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of C₁₀H₁₃N₃O₃

There total 1 articles about C₁₀H₁₃N₃O₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

4-methoxybenzoic acid hydrazide (3290-99-1) + methyl isocyanate (624-83-9) → C10H13N3O3 (129521-46-6)

Guidance literature:

In tetrahydrofuran; for 17h;

DOI:10.1021/jm00172a015

Reference yield: 86.0%

C10H13N3O3 (129521-46-6) → 5-(4-Methoxy-phenyl)-4-methyl-2,4-dihydro-[1,2,4]triazol-3-one (129521-49-9)

Guidance literature:

With sodium hydroxide; for 23h; Heating;

DOI:10.1021/jm00172a015

Reference yield:

C10H13N3O3 (129521-46-6) → 5-(4-Methoxy-phenyl)-2,4-dimethyl-2,4-dihydro-[1,2,4]triazol-3-one (129521-51-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 86 percent / aq. NaOH / 23 h / Heating

2: 36 percent / aq. NaOH / ethanol / 24 h

With sodium hydroxide; In ethanol;

DOI:10.1021/jm00172a015

upstream raw materials:

4-methoxybenzoic acid hydrazide

methyl isocyanate

Downstream raw materials:

5-(4-Methoxy-phenyl)-4-methyl-2,4-dihydro-[1,2,4]triazol-3-one

5-(4-Methoxy-phenyl)-2,4-dimethyl-2,4-dihydro-[1,2,4]triazol-3-one

Refernces