Thiazolo[5,4-f]quinoline (8CI,9CI)

Base Information

• Chemical Name: Thiazolo[5,4-f]quinoline (8CI,9CI)
• CAS No.: 234-48-0
• Molecular Formula: C₁₀H₆N₂S
• Molecular Weight: 186.237
• Hs Code.: 2934999090
• Mol file: 234-48-0.mol

Synonyms:1-Thia-3,6-diaza-1H-benz[e]indene

Chemical Property of Thiazolo[5,4-f]quinoline (8CI,9CI)

Chemical Property:

• PSA: 54.02000
• LogP: 2.84450

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Thiazolo[5,4-f]quinoline (8CI,9CI)

There total 4 articles about Thiazolo[5,4-f]quinoline (8CI,9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

6-nitrobenzo[d]thiazole (2942-06-5) → Thiazolochinolin (234-48-0)

Guidance literature:

Multi-step reaction with 2 steps

1: SnCl₂; aqueous HCl; methanol

2: sodium-salt of/the/ 3-nitro-benzenesulfonic acid; aqueous H₂SO₄

With hydrogenchloride; methanol; sulfuric acid; sodium 3-nitrobenzenesulfonate; tin(ll) chloride;

DOI:10.1039/jr9490000355

Reference yield:

1,3-benzothiazol-6-amine (533-30-2) → Thiazolochinolin (234-48-0)

Guidance literature:

Multi-step reaction with 2 steps

1: CHCl₃; bromine

2: sodium-salt of/the/ 3-nitro-benzenesulfonic acid; aqueous H₂SO₄

With chloroform; sulfuric acid; bromine; sodium 3-nitrobenzenesulfonate;

DOI:10.1039/jr9490000355

Reference yield:

1,3-benzothiazol-6-amine (533-30-2) + glycerol (56-81-5,25618-55-7,64333-26-2,8013-25-0) → Thiazolochinolin (234-48-0)

Guidance literature:

With sulfuric acid; sodium 3-nitrobenzenesulfonate;

DOI:10.1039/jr9490000355

upstream raw materials:

1,3-benzothiazol-6-amine

glycerol

6-amino-7-bromo-1,3-benzothiazole

6-nitrobenzo[d]thiazole