TETRT-BUTYL5-METHYL-1,4-DIAZEPANE-1-CARBOXYLATE

Base Information

• Chemical Name: TETRT-BUTYL5-METHYL-1,4-DIAZEPANE-1-CARBOXYLATE
• CAS No.: 194032-42-3
• Molecular Formula: C₁₁H₂₂N₂O₂
• Molecular Weight: 214.308
• Hs Code.: 2933990090
• Mol file: 194032-42-3.mol

Synonyms:tetrt-Butyl 5-methyl-1,4-diazepane-1-carboxylate;

Chemical Property of TETRT-BUTYL5-METHYL-1,4-DIAZEPANE-1-CARBOXYLATE

Chemical Property:

• Vapor Pressure: 0.00235mmHg at 25°C
• Refractive Index: 1.456
• Boiling Point: 288.3 °C at 760 mmHg
• PKA: 10.51±0.40(Predicted)
• Flash Point: 128.2 °C
• PSA: 41.57000
• Density: 0.98 g/cm³
• LogP: 1.87200
• Storage Temp.: 2-8°C(protect from light)

Purity/Quality:

99% ^*data from raw suppliers

tert-Butyl5-methyl-1,4-diazepane-1-carboxylate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: tert-Butyl 5-methyl-1,4-diazepane-1-carboxylate is a reagent in the preparation of CXCR4 receptor antagonists as well as isoquinoline derivatives of drugs, shown to have biological activity. It is also a homopiperazine derivative with potential antibiotic properties.

Technology Process of TETRT-BUTYL5-METHYL-1,4-DIAZEPANE-1-CARBOXYLATE

There total 1 articles about TETRT-BUTYL5-METHYL-1,4-DIAZEPANE-1-CARBOXYLATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 17.0%

di-tert-butyl dicarbonate (24424-99-5) + hexahydro-5-methyl-1H-1,4-diazepine (22777-05-5) → tert-butyl 5-methyl-1,4-diazepane-1-carboxylate (194032-42-3,1260619-37-1)

Guidance literature:

With triethylamine; In dichloromethane; N,N-dimethyl-formamide; at 0 ℃; for 3h;

upstream raw materials:

di-tert-butyl dicarbonate

hexahydro-5-methyl-1H-1,4-diazepine

Refernces