Boc-βAla-Δ^ZTrp-Met-Asp-Phe-NH2

Base Information

• Chemical Name: Boc-βAla-Δ^ZTrp-Met-Asp-Phe-NH2
• CAS No.: 207744-21-6
• Molecular Formula: C₃₇H₄₇N₇O₉S
• Molecular Weight: 765.888
• Mol file: 207744-21-6.mol

Synonyms:Boc-βAla-Δ^ZTrp-Met-Asp-Phe-NH2

Chemical Property of Boc-βAla-Δ^ZTrp-Met-Asp-Phe-NH2

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Boc-βAla-Δ^ZTrp-Met-Asp-Phe-NH2

There total 1 articles about Boc-βAla-Δ^ZTrp-Met-Asp-Phe-NH2 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

pentagastrin (5534-95-2,77055-37-9,7488-96-2) → Boc-βAla-ΔZTrp-Met-Asp-Phe-NH2 (207744-21-6)

Guidance literature:

With (S)-tryptophan 2',3'-oxidase from Chromobacterium violaceum (ATCC 12472); In various solvent(s); at 30 ℃; for 20h;

DOI:10.1016/S0040-4039(98)00377-3

Reference yield: 80.0%

Boc-βAla-ΔZTrp-Met-Asp-Phe-NH2 (207744-21-6) → Boc-βAla-[2',3'-2H2]-Trp-Met-Asp-Phe-NH2 + Boc-βAla-[2',3'-2H2]-(S)Trp-Met-Asp-Phe-NH2

Guidance literature:

With hydrogen; ; In methanol; at 20 ℃; for 20h; under 11400 Torr; Yields of byproduct given;

DOI:10.1016/S0040-4039(98)00377-3

Reference yield:

Boc-βAla-ΔZTrp-Met-Asp-Phe-NH2 (207744-21-6) → pentagastrin (5534-95-2,77055-37-9,7488-96-2) + Boc-βAla-(R)Trp-Met-Asp-Phe-NH2 (77055-37-9,7488-96-2)

Guidance literature:

With hydrogen; (S,S)-2,3-O-isopropylidene-2,3-dihydroxy-1,4-bis(diphenylphosphino)butane; rhodium; In methanol; at 20 ℃; Further Variations:; Catalysts; Product distribution;

DOI:10.1016/S0040-4020(00)00329-X

upstream raw materials:

pentagastrin

Downstream raw materials:

pentagastrin

Boc-βAla-(R)Trp-Met-Asp-Phe-NH2

Refernces

• 1、 Hammadi, Akli,Meunier, Gilles,Menez, Andre,Genet, Roger. "Diastereoselective deuteration of (Z)-α,β-dehydrotryptophanyl- containing biological peptides controlled by chiral rhodium catalysts". . p. 2955 - 2958. Retrieved 2007/10/03.