2-NAPHTHALENECARBOXYLIC ACID, 6-NITRO

Base Information

• Chemical Name: 2-NAPHTHALENECARBOXYLIC ACID, 6-NITRO
• CAS No.: 5783-91-5
• Molecular Formula: C₁₁H₇NO₄
• Molecular Weight: 217.181
• Mol file: 5783-91-5.mol

Synonyms:6-nitro-[2]naphthoic acid

Chemical Property of 2-NAPHTHALENECARBOXYLIC ACID, 6-NITRO

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-NAPHTHALENECARBOXYLIC ACID, 6-NITRO

There total 5 articles about 2-NAPHTHALENECARBOXYLIC ACID, 6-NITRO which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

6-nitro-[2]naphthonitrile → 6-nitro-[2]naphthoic acid (5783-91-5)

Guidance literature:

With sulfuric acid; acetic acid;

DOI:10.1021/ja01516a030 DOI:10.1002/jps.3030411210

Reference yield:

6-Nitro-2-naphthalincarbonsaeuremethylester (5042-95-5) → 6-nitro-[2]naphthoic acid (5783-91-5)

Guidance literature:

With potassium hydroxide; In ethanol;

Reference yield:

2-acetylaminonaphthalene (581-97-5) → 6-nitro-[2]naphthoic acid (5783-91-5)

Guidance literature:

Multi-step reaction with 4 steps

1: (i) (nitration), (ii) (hydrolysis)

2: (i) NaNO₂, aq. HCl, (ii) /BRN= 4652394/, CuCN

3: (i) aq. H₂SO₄, AcOH, (ii) /BRN= 102415/, dioxane

4: KOH / ethanol

With potassium hydroxide; In ethanol;

upstream raw materials:

6-Nitro-2-naphthalincarbonsaeuremethylester

2-acetylaminonaphthalene

6-nitro-2-naphthylamine

Downstream raw materials:

6-amino-2-naphthoic acid

Refernces

• 1、 STAPLETON,WHITE. "Routes to the synthesis of 6-amino-2-naphthoic acid.". . p. 657 - 658. Retrieved 2007/10/06.