N, N-diisopropyl-O-benzoyl hydroxylamine

Base Information

• Chemical Name: N, N-diisopropyl-O-benzoyl hydroxylamine
• CAS No.: 92197-18-7
• Molecular Formula: C₁₃H₁₉NO₂
• Molecular Weight: 221.299
• Mol file: 92197-18-7.mol

Synonyms:N, N-diisopropyl-O-benzoyl hydroxylamine

Chemical Property of N, N-diisopropyl-O-benzoyl hydroxylamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N, N-diisopropyl-O-benzoyl hydroxylamine

There total 1 articles about N, N-diisopropyl-O-benzoyl hydroxylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

diisopropylamine (108-18-9) + dibenzoyl peroxide (94-36-0) → N, N-diisopropyl-O-benzoyl hydroxylamine (92197-18-7)

Guidance literature:

With dipotassium hydrogenphosphate; In N,N-dimethyl-formamide; at 20 ℃; for 24h;

DOI:10.1021/jo051999h

Reference yield: 94.0%

N, N-diisopropyl-O-benzoyl hydroxylamine (92197-18-7) + 5,5-dimethyl-2-(4-formylphenyl)-1,3,2-dioxaborinane (128376-65-8) → 4-(diisopropylamino)benzaldehyde

Guidance literature:

With copper (I) tert-butoxide; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; lithium tert-butoxide; In 2,2,4-trimethylpentane; toluene; at 60 ℃; Inert atmosphere;

DOI:10.1002/anie.201200480

Reference yield: 94.0%

N, N-diisopropyl-O-benzoyl hydroxylamine (92197-18-7) + 2-(4-bromophenyl)-5,5-dimethyl-1,3,2-dioxaborinane (183677-71-6) → 4-bromo-N,N-bis(propan-2-yl)aniline (13330-86-4)

Guidance literature:

With copper(I) triflate benzene complex; cesium fluoride; 1,1'-(oxydi-2,1-phenylene)bis[1,1-dicyclohexylphosphine]; In tetrahydrofuran; at 66 ℃; Inert atmosphere;

DOI:10.1039/c5cc03565a

upstream raw materials:

diisopropylamine

dibenzoyl peroxide

Downstream raw materials:

N,N-diisopropyl(2-methylphenyl)amine

N,N-bis(1-methylethyl)-4-chlorobenzenamine

ethyl 4-(diisopropylamino)-3-nitrobenzoate

N,N-diisopropyl-3,5-bis(trifluoromethyl)aniline

Refernces

• 1、 Bouarfa, Salima,Gra?l, Simon,Ivanova, Maria,Langlais, Timothy,Bentabed-Ababsa, Ghenia,Lassagne, Frédéric,Erb, William,Roisnel, Thierry,Dorcet, Vincent,Knochel, Paul,Mongin, Florence. "Copper- and Cobalt-Catalyzed Syntheses of Thiophene-Based Tertiary Amines". . p. 3244 - 3258. Retrieved 2019/06/08.
• 2、 Miki, Yuya,Hirano, Koji,Satoh, Tetsuya,Miura, Masahiro. "Copper-catalyzed enantioselective formal hydroamination of oxa- and azabicyclic alkenes with hydrosilanes and hydroxylamines". supporting information. p. 1498 - 1501. Retrieved 2014/04/03.