Technology Process of Nα-(N-benzyloxycarbonyl-β-alanyl)-histidine
There total 10 articles about Nα-(N-benzyloxycarbonyl-β-alanyl)-histidine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
N-benzyl-trimethylammonium hydroxide;
In
methanol; ethanol; water;
at 10 - 50 ℃;
for 2h;
pH=6.4;
- Guidance literature:
-
benzyl chloroformate; Carnosine;
With
sodium hydroxide;
In
water; acetone;
at 0 - 25 ℃;
for 16h;
pH=12 - 13;
With
hydrogenchloride;
In
water; acetone;
pH=2 - 2.5;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: diethyl ether; PCl5 / 0 °C
2: anfangs unter Kuehlung
3: ethanol; 42 percent aqueous hydrazine hydrate
4: water; HCl; acetic acid; NaNO2 / Umsetzen des erhaltenen Azids mit L-Histidin-methylester und anschliessendes Behandeln mit wss.NaOH
With
hydrogenchloride; diethyl ether; ethanol; phosphorus pentachloride; water; hydrazine hydrate; acetic acid; sodium nitrite;
