AMYLOID BETA-PROTEIN (29-40)

Base Information

• Chemical Name: AMYLOID BETA-PROTEIN (29-40)
• CAS No.: 184865-04-1
• Molecular Formula: C49H88 N12 O13 S
• Molecular Weight: 1085.36
• Mol file: 184865-04-1.mol

Synonyms:11: PN: WO2008156621SEQID: 2 claimed sequence; 14: PN: WO2009004494 SEQID: 9 claimed sequence; 19:PN: WO2008060364 SEQID: 47 unclaimed sequence; 1: PN: EP1481987 SEQID: 2claimed protein; 1: PN: WO2009033743 SEQID: 1 claimed protein; 2: PN:DE19856261 SEQID: 2 claimed protein; 2: PN: WO2009048539 SEQID: 2 unclaimedsequence; 4: PN: WO2005081872 SEQID: 4 claimed sequence; 59: PN: WO2006018418SEQID: 24 claimed sequence; 5: PN: WO2007068411 SEQID: 6 unclaimed sequence; 5:PN: WO2007068412 SEQID: 5 claimed sequence; 6: PN: EP2009445 SEQID: 9 claimedprotein; 7: PN: EP2149380 SEQID: 7 claimed sequence; 8: PN: WO2010012749 SEQID:7 unclaimed protein; b-Amyloid peptide Ab(29-40) (synthetic)

Chemical Property of AMYLOID BETA-PROTEIN (29-40)

Chemical Property:

• PSA: 408.72000
• LogP: 3.13620

Purity/Quality:

99% ^*data from raw suppliers

β-Amyloid(29-40) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of AMYLOID BETA-PROTEIN (29-40)

There total 3 articles about AMYLOID BETA-PROTEIN (29-40) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

amyloid-β40 → H2N-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-OH + AIIGLMVGGVV (184865-04-1) + Aβ1?5 (118427-80-8) + Aβ6?16

Guidance literature:

With formic acid; trypsin; at 37 ℃; for 3h; Enzymatic reaction;

DOI:10.1016/j.ica.2017.07.031

Reference yield:

amyloid beta (1-40) peptide → H2N-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-OH + AIIGLMVGGVV (184865-04-1) + Aβ1?5 (118427-80-8) + amyloid beta (1-16) peptide + amyloid beta (17-40) peptide + Aβ [6-16]

Guidance literature:

With trypsin; In dimethyl sulfoxide; at 37 ℃; for 12h;

DOI:10.1002/rcm.7007

Reference yield:

R-sulforaphane (142825-10-3) + amyloid beta (1-40) peptide → H2N-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-OH + AIIGLMVGGVV (184865-04-1) + Aβ1?5 (118427-80-8) + amyloid beta (1-16) peptide modified with L-sulforaphane at Asp-1 + amyloid beta (1-16) peptide modified with L-sulforaphane at Lys-16 + amyloid beta (1-16) peptide + amyloid beta (1-28) peptide modified with L-sulforaphane at Asp-1 + amyloid beta (17-40) peptide modified with L-sulforaphane at Lys-28 + amyloid beta (17-40) peptide + amyloid beta (6-28) peptide modified with L-sulforaphane at Lys-16 + amyloid beta (6-40) peptide modified with L-sulforaphane at Lys-28 + C63H92N20O20S2 + C33H51N9O11S2 + C67H103N15O20S2 + Aβ [6-16]

Guidance literature:

With trypsin; In dimethyl sulfoxide; at 37 ℃; for 12h;

DOI:10.1002/rcm.7007

upstream raw materials:

R-sulforaphane

Refernces

• 1、 Nagaveni,Lakshmi,Prabhakar. "Sulforaphane interaction with amyloid beta 1-40 peptide studied by electrospray ionization mass spectrometry". . p. 2171 - 2180. Retrieved 2014/11/27.