Technology Process of [2-(2,2-dibromovinyl)-1-phenylcyclopropyl]benzene
There total 5 articles about [2-(2,2-dibromovinyl)-1-phenylcyclopropyl]benzene which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
carbon tetrabromide;
With
triphenylphosphine; zinc;
In
dichloromethane;
at 20 ℃;
for 20h;
2,2-diphenylcyclopropanecarbaldehyde;
In
dichloromethane;
at 20 ℃;
for 20h;
DOI:10.1021/jo062448+
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: copper acetoacetate / 1,2-dichloro-ethane / 15 h / 20 °C
2.1: 3.15 g / potassium hydroxide / H2O; methanol / 12 h / 20 °C
3.1: 28 percent / LiAlH4 / tetrahydrofuran / 1 h / 0 - 20 °C
4.1: 85 percent / pyridinium chlorochromate / CH2Cl2 / 3 h / 20 °C
5.1: triphenylphosphine; zinc / CH2Cl2 / 20 h / 20 °C
5.2: 93 percent / CH2Cl2 / 20 h / 20 °C
With
potassium hydroxide; lithium aluminium tetrahydride; copper acetyl-acetate; triphenylphosphine; pyridinium chlorochromate; zinc;
In
tetrahydrofuran; methanol; dichloromethane; water; 1,2-dichloro-ethane;
DOI:10.1021/jo062448+
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: 85 percent / pyridinium chlorochromate / CH2Cl2 / 3 h / 20 °C
2.1: triphenylphosphine; zinc / CH2Cl2 / 20 h / 20 °C
2.2: 93 percent / CH2Cl2 / 20 h / 20 °C
With
triphenylphosphine; pyridinium chlorochromate; zinc;
In
dichloromethane;
DOI:10.1021/jo062448+
