1-acetoxy-2-chlorocyclohexanecarboxylic acid

Base Information

• Chemical Name: 1-acetoxy-2-chlorocyclohexanecarboxylic acid
• CAS No.: 108791-50-0
• Molecular Formula: C₉H₁₃ClO₄
• Molecular Weight: 220.653
• Mol file: 108791-50-0.mol

Synonyms:1-acetoxy-2-chlorocyclohexanecarboxylic acid

Chemical Property of 1-acetoxy-2-chlorocyclohexanecarboxylic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-acetoxy-2-chlorocyclohexanecarboxylic acid

There total 3 articles about 1-acetoxy-2-chlorocyclohexanecarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 17.0%

cyclohexene-1-carboxylic acid (636-82-8) → 2,2,6,6-tetrachlorocyclohexanone (3776-30-5) + 1,2-dichlorocyclohexanecarboxylic acid (108791-49-7) + 1-acetoxy-2-chlorocyclohexanecarboxylic acid (108791-50-0)

Guidance literature:

With manganese triacetate; lithium chloride; In acetic acid; Heating;

DOI:10.1246/bcsj.59.3153

Reference yield: 7.0%

cyclohexene-1-carboxylic acid (636-82-8) + Mangantriacetat → 2,2,6,6-tetrachlorocyclohexanone (3776-30-5) + 1,2-dichlorocyclohexanecarboxylic acid (108791-49-7) + 1-acetoxy-2-chlorocyclohexanecarboxylic acid (108791-50-0)

Guidance literature:

With lithium chloride; In acetic acid; Heating;

DOI:10.1246/bcsj.59.3153

Reference yield:

manganese(II) acetate (638-38-0,993-02-2,2180-18-9,15411-95-7,22981-23-3,27004-39-3) + acetic anhydride (108-24-7) + 1,2-dichlorocyclohexanecarboxylic acid (108791-49-7) → 1-acetoxy-2-chlorocyclohexanecarboxylic acid (108791-50-0)

Guidance literature:

In acetic acid; for 3h; Heating;

DOI:10.1246/bcsj.59.3153

upstream raw materials:

cyclohexene-1-carboxylic acid

manganese(II) acetate

acetic anhydride

1,2-dichlorocyclohexanecarboxylic acid

Refernces