benzyl N-[5-[[4-[5-[[4-[5-[acetyl(hydroxy)amino]pentylamino]-4-oxo-butanoyl]-hydroxy-amino]pentylamino]-4-oxo-butanoyl]-hydroxy-amino]pentyl]carbamate

Base Information

• Chemical Name: benzyl N-[5-[[4-[5-[[4-[5-[acetyl(hydroxy)amino]pentylamino]-4-oxo-butanoyl]-hydroxy-amino]pentylamino]-4-oxo-butanoyl]-hydroxy-amino]pentyl]carbamate
• CAS No.: 402913-84-2
• Molecular Formula: C₃₃H₅₄N₆O₁₀
• Molecular Weight: 694.826
• Mol file: 402913-84-2.mol

Synonyms:1-Carbobenzoxyamino-6,17-dihydroxy-7,10,18,21-tetraoxy-27-(N-acetyl-hydroxyamino)-6,11,17,22-tetraaza-hepteikosan

Chemical Property of benzyl N-[5-[[4-[5-[[4-[5-[acetyl(hydroxy)amino]pentylamino]-4-oxo-butanoyl]-hydroxy-amino]pentylamino]-4-oxo-butanoyl]-hydroxy-amino]pentyl]carbamate

Chemical Property:

Purity/Quality:

99.9% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of benzyl N-[5-[[4-[5-[[4-[5-[acetyl(hydroxy)amino]pentylamino]-4-oxo-butanoyl]-hydroxy-amino]pentylamino]-4-oxo-butanoyl]-hydroxy-amino]pentyl]carbamate

There total 8 articles about benzyl N-[5-[[4-[5-[[4-[5-[acetyl(hydroxy)amino]pentylamino]-4-oxo-butanoyl]-hydroxy-amino]pentylamino]-4-oxo-butanoyl]-hydroxy-amino]pentyl]carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-(Carbobenzoxyamino)-5-(hydroxyamino)pentane (91905-05-4) → 1-Carbobenzoxyamino-6,17-dihydroxy-7,10,18,21-tetraoxy-27-(N-acetyl-hydroxyamino)-6,11,17,22-tetraaza-hepteikosan (402913-84-2)

Guidance literature:

Multi-step reaction with 3 steps

1: Py

2: acetic anhydride / 5 h / 95 - 100 °C

3: (i) H₂, Pd-C, MeOH, (ii) /BRN= 898057/

With pyridine; In acetic anhydride;

DOI:10.1002/hlca.19620450228

Reference yield:

1-Carbobenzoxyamino-5-nitro-pentan (92034-20-3) → 1-Carbobenzoxyamino-6,17-dihydroxy-7,10,18,21-tetraoxy-27-(N-acetyl-hydroxyamino)-6,11,17,22-tetraaza-hepteikosan (402913-84-2)

Guidance literature:

Multi-step reaction with 4 steps

1: aq. NH₄Cl, Zn / ethanol

2: Py

3: acetic anhydride / 5 h / 95 - 100 °C

4: (i) H₂, Pd-C, MeOH, (ii) /BRN= 898057/

With pyridine; ammonium chloride; zinc; In ethanol; acetic anhydride;

DOI:10.1002/hlca.19620450228

Reference yield:

5-nitropentylammonium chloride → 1-Carbobenzoxyamino-6,17-dihydroxy-7,10,18,21-tetraoxy-27-(N-acetyl-hydroxyamino)-6,11,17,22-tetraaza-hepteikosan (402913-84-2)

Guidance literature:

Multi-step reaction with 5 steps

1: aq. NaOH

2: aq. NH₄Cl, Zn / ethanol

3: Py

4: acetic anhydride / 5 h / 95 - 100 °C

5: (i) H₂, Pd-C, MeOH, (ii) /BRN= 898057/

With pyridine; sodium hydroxide; ammonium chloride; zinc; In ethanol; acetic anhydride;

DOI:10.1002/hlca.19620450228

upstream raw materials:

N⁽¹⁾-Benzyloxycarbonyl-6,17-dihydroxy-7,10,18-trioxo-6,11,17-triazanonadecylamin

[5-(3,6-dioxo-[1,2]oxazinan-2-yl)-pentyl]-carbamic acid benzyl ester

1-(Carbobenzoxyamino)-5-(hydroxyamino)pentane

1-Carbobenzoxyamino-5-nitro-pentan

Downstream raw materials:

deferoxamine