di[2-(1-adamantyloxy)ethyl] tosyloxymethylphosphonate

Base Information

• Chemical Name: di[2-(1-adamantyloxy)ethyl] tosyloxymethylphosphonate
• CAS No.: 1373943-95-3
• Molecular Formula: C₃₂H₄₇O₈PS
• Molecular Weight: 622.76
• Mol file: 1373943-95-3.mol

Synonyms:di[2-(1-adamantyloxy)ethyl] tosyloxymethylphosphonate

Chemical Property of di[2-(1-adamantyloxy)ethyl] tosyloxymethylphosphonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of di[2-(1-adamantyloxy)ethyl] tosyloxymethylphosphonate

There total 2 articles about di[2-(1-adamantyloxy)ethyl] tosyloxymethylphosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(dichlorophosphoryl)methyl 4-methylbenzenesulfonate + 2-(1-adamantyloxy)ethan-1-ol (775-66-6) → di[2-(1-adamantyloxy)ethyl] tosyloxymethylphosphonate (1373943-95-3)

Guidance literature:

With triethylamine; In diethyl ether; at 0 ℃; for 12h; Inert atmosphere;

DOI:10.1134/S1070363212050052

Reference yield:

diethyl (p-toluenesulfonyloxymethane)phosphonate (31618-90-3) → di[2-(1-adamantyloxy)ethyl] tosyloxymethylphosphonate (1373943-95-3)

Guidance literature:

Multi-step reaction with 3 steps

1: dichloromethane / 16 h / 20 °C / Inert atmosphere

2: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 6 h / 0 - 5 °C / Inert atmosphere

3: triethylamine / diethyl ether / 12 h / 0 °C / Inert atmosphere

With oxalyl dichloride; triethylamine; N,N-dimethyl-formamide; In diethyl ether; dichloromethane;

DOI:10.1134/S1070363212050052

Reference yield:

di[2-(1-adamantyloxy)ethyl] tosyloxymethylphosphonate (1373943-95-3) + C33H29N3O4 → C58H68N3O9P

Guidance literature:

C₃₃H₂₉N₃O₄; With sodium hydride; In dimethyl sulfoxide; mineral oil; at 20 ℃; for 3h; Inert atmosphere;

di[2-(1-adamantyloxy)ethyl] tosyloxymethylphosphonate; In dimethyl sulfoxide; mineral oil; at 20 ℃; for 12h; Inert atmosphere;

DOI:10.1134/S1070363215020097

upstream raw materials:

2-(1-adamantyloxy)ethan-1-ol

diethyl (p-toluenesulfonyloxymethane)phosphonate

Refernces