Technology Process of KF49199
There total 5 articles about KF49199 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium thiophenolate;
In
N,N-dimethyl-formamide;
at 150 - 160 ℃;
for 0.333333h;
DOI:10.1021/jm00062a005
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 82 percent / K2CO3 / dimethylformamide / 0.5 h / 60 °C
2: 54 percent / sodium thiophenoxide / dimethylformamide / 0.33 h / 150 - 160 °C
With
sodium thiophenolate; potassium carbonate;
In
N,N-dimethyl-formamide;
DOI:10.1021/jm00062a005
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 1-<3-(dimethylamino)propyl>-3-ethylcarbodiimide hydrochloride, 4-(N,N-dimethylamino)pyridine, imidazole / dimethylformamide / 3 h / Ambient temperature
2: 4 N aq. NaOH / methanol / 2 h / 60 °C
3: 82 percent / K2CO3 / dimethylformamide / 0.5 h / 60 °C
4: 54 percent / sodium thiophenoxide / dimethylformamide / 0.33 h / 150 - 160 °C
With
1H-imidazole; dmap; sodium hydroxide; sodium thiophenolate; potassium carbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;
In
methanol; N,N-dimethyl-formamide;
DOI:10.1021/jm00062a005