Atracurium

Base Information

• Chemical Name: Atracurium
• CAS No.: 64228-79-1
• Molecular Formula: C53H72 N2 O12
• Molecular Weight: 929.161
• DSSTox Substance ID: DTXSID9043726
• Nikkaji Number: J292.641E
• Wikidata: Q27098039
• NCI Thesaurus Code: C76068
• RXCUI: 1218
• Pharos Ligand ID: 39K853FFQ9TT
• Metabolomics Workbench ID: 43037
• ChEMBL ID: CHEMBL1360
• Mol file: 64228-79-1.mol

Synonyms:33 A 74;A 74, 33;Atracurium;Atracurium Besilate;Atracurium Besylate;Atracurium Dibesylate;Besilate, Atracurium;BW 33A;BW-33A;BW33A;Relatrac;Tracrium

Chemical Property of Atracurium

Chemical Property:

• Melting Point: 185-194 ºC
• PSA: 126.44000
• LogP: 7.98310
• Storage Temp.: -20°C Freezer
• Solubility.: DMSO (Slightly), Methanol (Slightly)
• XLogP3: 7.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 12
• Rotatable Bond Count: 26
• Exact Mass: 928.50852574
• Heavy Atom Count: 67
• Complexity: 1390

Purity/Quality:

99% ^*data from raw suppliers

Atracurium besylate European Pharmacopoeia (EP) Reference Standard ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C[N+]1(CCC2=CC(=C(C=C2C1CC3=CC(=C(C=C3)OC)OC)OC)OC)CCC(=O)OCCCCCOC(=O)CC[N+]4(CCC5=CC(=C(C=C5C4CC6=CC(=C(C=C6)OC)OC)OC)OC)C
• Recent ClinicalTrials: Pain Management of Pecto-intercostal Fascial Block Versus Intravenous Fentanyl After Pediatric Cardiac Surgery
• Recent EU Clinical Trials: A randomised assessor blinded study to examine the role of skin testing in the prediction of peri-operative anaphylaxis and its correlation with mast cell tryptase and total IgE.
• Uses: Atracurium besylate is a neuromuscular-blocking drug or skeletal muscle relaxant in the category ofnon-depolarizing neuromuscular-blocking drugs, used adjunctively in anesthesiato facilitate endotracheal intubation and to provide skeletal muscle relaxationduring surgery or mechanical ventilation.The drug atracurium besylate can be used most advantageously if muscle twitch response to peripheral nerve stimulation is monitored.