Technology Process of C19H18F3N3O5S
There total 10 articles about C19H18F3N3O5S which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
water; sodium hydroxide;
In
1,4-dioxane;
at 20 ℃;
for 2h;
DOI:10.1002/cmdc.201200386
- Guidance literature:
-
Multi-step reaction with 10 steps
1.1: nitromethane / 0.5 h / -40 °C
1.2: 1 h / 110 °C
2.1: sodium hydroxide; potassium permanganate / water / 7 h / 0 - 80 °C
2.2: pH 1
3.1: sulfuric acid / water / 6 h / 140 °C
3.2: 0.5 h / 0 °C
4.1: 2 h / Reflux
5.1: thionyl chloride / 75 °C
6.1: triethylamine / acetonitrile / 0.5 h / 20 °C
7.1: potassium carbonate / acetonitrile / 2 h / 75 °C
8.1: sodium tetrahydroborate / methanol / 0.08 h
9.1: potassium carbonate / acetonitrile / 2 h / 70 °C
10.1: sodium hydroxide; water / 1,4-dioxane / 2 h / 20 °C
With
sodium tetrahydroborate; potassium permanganate; thionyl chloride; sulfuric acid; water; potassium carbonate; triethylamine; sodium hydroxide;
In
1,4-dioxane; methanol; nitromethane; water; acetonitrile;
DOI:10.1002/cmdc.201200386
- Guidance literature:
-
Multi-step reaction with 7 steps
1: 2 h / Reflux
2: thionyl chloride / 75 °C
3: triethylamine / acetonitrile / 0.5 h / 20 °C
4: potassium carbonate / acetonitrile / 2 h / 75 °C
5: sodium tetrahydroborate / methanol / 0.08 h
6: potassium carbonate / acetonitrile / 2 h / 70 °C
7: sodium hydroxide; water / 1,4-dioxane / 2 h / 20 °C
With
sodium tetrahydroborate; thionyl chloride; water; potassium carbonate; triethylamine; sodium hydroxide;
In
1,4-dioxane; methanol; acetonitrile;
DOI:10.1002/cmdc.201200386