2,3-dimethoxy-benzylamine; hydrochloride

Base Information

• Chemical Name: 2,3-dimethoxy-benzylamine; hydrochloride
• CAS No.: 56221-31-9
• Molecular Formula: C₉H₁₃NO₂*ClH
• Molecular Weight: 203.669
• Mol file: 56221-31-9.mol

Synonyms:2,3-dimethoxy-benzylamine; hydrochloride

Chemical Property of 2,3-dimethoxy-benzylamine; hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,3-dimethoxy-benzylamine; hydrochloride

There total 2 articles about 2,3-dimethoxy-benzylamine; hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

oxime of 2,3-dimethoxy-benzaldehyde (5470-95-1) → 2,3-dimethoxy-benzylamine; hydrochloride (56221-31-9)

Guidance literature:

With hydrogenchloride; 5%-palladium/activated carbon; hydrogen; In ethanol; at 20 ℃; under 760.051 Torr;

DOI:10.1002/adsc.201300832

Reference yield:

2,3-dimethyoxybenzaldehyde (86-51-1) → 2,3-dimethoxy-benzylamine; hydrochloride (56221-31-9)

Guidance literature:

Multi-step reaction with 2 steps

1: hydroxylamine hydrochloride; sodium acetate / ethanol / 6 h / 20 °C

2: hydrogenchloride; hydrogen; 5%-palladium/activated carbon / ethanol / 20 °C / 760.05 Torr

With hydrogenchloride; 5%-palladium/activated carbon; hydroxylamine hydrochloride; hydrogen; sodium acetate; In ethanol;

DOI:10.1002/adsc.201300832

Reference yield:

2,3-dimethoxy-benzylamine; hydrochloride (56221-31-9) → N,N-diethyl-N'-[8-(2,3-dimethoxy-benzyl)-nortropane-3endo-yl]-ethylenediamine (102943-88-4)

Guidance literature:

Multi-step reaction with 2 steps

1: water / Erhitzen des Reaktionsgemisches mit wss. Salzsaeure

2: ethanol; platinum / Hydrogenation

With ethanol; water; platinum;

upstream raw materials:

2,3-dimethyoxybenzaldehyde

oxime of 2,3-dimethoxy-benzaldehyde

Downstream raw materials:

8-(2,3-dimethoxy-benzyl)-nortropan-3-one

N,N-diethyl-N'-[8-(2,3-dimethoxy-benzyl)-nortropane-3endo-yl]-ethylenediamine

Refernces