(S)-6-BROMO-2-AMINOTETRALIN

Base Information

• Chemical Name: (S)-6-BROMO-2-AMINOTETRALIN
• CAS No.: 176707-78-1
• Molecular Formula: C₁₀H₁₂BrN
• Molecular Weight: 226.116
• Hs Code.: 2921450090
• Mol file: 176707-78-1.mol

Synonyms:2-Naphthalenamine,6-bromo-1,2,3,4-tetrahydro-, (S)-;(S)-(6-Bromo-1,2,3,4-tetrahydro-2-naphthyl)amine;

Chemical Property of (S)-6-BROMO-2-AMINOTETRALIN

Chemical Property:

• Vapor Pressure: 0.00125mmHg at 25°C
• Refractive Index: 1.593
• Boiling Point: 298.7 °C at 760mmHg
• PKA: 10.02±0.20(Predicted)
• Flash Point: 134.5 °C
• PSA: 26.02000
• Density: 1.413 g/cm³
• LogP: 2.96540

Purity/Quality:

99.3% ^*data from raw suppliers

(2S)-6-BROMO-2-1,2,3,4-TETRAHYDRONAPHTHYLAMINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (S)-6-BROMO-2-AMINOTETRALIN

There total 8 articles about (S)-6-BROMO-2-AMINOTETRALIN which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

(S)-N-(6-bromo-1,2,3,4-tetrahydronaphthalen-2-yl)benzamide → (S)-6-bromo-1,2,3,4-tetrahydronaphthalen-2-amine (176707-78-1)

Guidance literature:

With methanesulfonic acid; acetic acid; In water; at 160 ℃; for 24h; under 5250.53 Torr; Autoclave; Inert atmosphere;

Reference yield: 93.0%

N-((R)-6-Bromo-1,2,3,4-tetrahydro-naphthalen-2-yl)-benzamide → 2-Amino-6-bromo tetralin (167172-92-1,176707-78-1)

Guidance literature:

With methanesulfonic acid; In acetic acid; at 160 ℃; for 24h;

DOI:10.1021/jo00119a008

Reference yield: 92.5%

(R)-2-Azido-6-bromo-1,2,3,4-tetrahydro-naphthalene → 2-Amino-6-bromo tetralin (167172-92-1,176707-78-1)

Guidance literature:

With [2,2]bipyridinyl; sodium tetrahydroborate; cobalt(II) bromide; In ethanol; for 2h; Ambient temperature;

DOI:10.1021/jo00119a008

upstream raw materials:

6-bromo-2-oximino-1,2,3,4-tetrahydronaphthalene

6-bromo-2-tetralone

Refernces

• 1、 -. "CARBOXAMIDES AS UBIQUITIN-SPECIFIC PROTEASE INHIBITORS". Paragraph 00185. . Retrieved 2019/02/25.
• 2、 -. "MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO". Page/Page column 62-63. . Retrieved 2016/04/26.