methyl iminothioveratramide

Base Information

• Chemical Name: methyl iminothioveratramide
• CAS No.: 263747-40-6
• Molecular Formula: C₁₀H₁₃NO₂S
• Molecular Weight: 211.285
• Mol file: 263747-40-6.mol

Synonyms:methyl iminothioveratramide

Chemical Property of methyl iminothioveratramide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of methyl iminothioveratramide

There total 1 articles about methyl iminothioveratramide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

3,4-dimethoxy-thiobenzamide (58952-14-0) + methyl iodide (74-88-4) → methyl iminothioveratramide (263747-40-6)

Guidance literature:

With potassium hydroxide; In 1,4-dioxane; at 25 ℃; for 4.5h;

DOI:10.1007/BF02252108

Reference yield: 65.0%

methyl iminothioveratramide (263747-40-6) → veratronitrile (2024-83-1)

Guidance literature:

With potassium hydroxide; In 1,4-dioxane; at 20 - 25 ℃; for 3h;

DOI:10.1023/B:COHC.0000003514.72510.ac

Reference yield: 65.0%

anthranilic acid (118-92-3,159201-01-1,50816-84-7,80206-34-4,104809-47-4) + methyl iminothioveratramide (263747-40-6) → 2-(31,41-dimethoxyphenyl)quinazol-4-one (132982-03-7)

Guidance literature:

at 140 - 150 ℃; for 2h;

DOI:10.1007/BF02252108

upstream raw materials:

3,4-dimethoxy-thiobenzamide

methyl iodide

Downstream raw materials:

2-(3¹,4¹-dimethoxyphenyl)quinazol-4-one

veratronitrile

Veratric acid

Refernces

• 1、 Sayfullina,Tashmukhamedova,Shakhidoyatov. "Effect of crown ether macrocycle on the methylation of the thioamide derivatives of benzo-15-crown-5 and veratrole". . p. 998 - 1001. Retrieved 2007/10/03.