Technology Process of 2-amino-6-benzyloxy-9-<2'-(2,2-dimethyl-1,3-dioxan-5-yl)-ethyl>-9H-purine
There total 6 articles about 2-amino-6-benzyloxy-9-<2'-(2,2-dimethyl-1,3-dioxan-5-yl)-ethyl>-9H-purine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 41 percent / p-TsOH*H2O / tetrahydrofuran / 0.5 h / Ambient temperature
2: 87 percent / CBr4, PPh3 / dimethylformamide / 0.5 h / 0 °C
3: 64 percent / K2CO3 / dimethylformamide / 5 h / Ambient temperature
With
carbon tetrabromide; potassium carbonate; toluene-4-sulfonic acid; triphenylphosphine;
In
tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1021/jm00392a020
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 100 percent / sodium borohydride, MeOH / 2-methyl-propan-2-ol / 0.5 h / Heating
2: 41 percent / p-TsOH*H2O / tetrahydrofuran / 0.5 h / Ambient temperature
3: 87 percent / CBr4, PPh3 / dimethylformamide / 0.5 h / 0 °C
4: 64 percent / K2CO3 / dimethylformamide / 5 h / Ambient temperature
With
methanol; sodium tetrahydroborate; carbon tetrabromide; potassium carbonate; toluene-4-sulfonic acid; triphenylphosphine;
In
tetrahydrofuran; N,N-dimethyl-formamide; tert-butyl alcohol;
DOI:10.1021/jm00392a020
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 64 percent / K2CO3 / dimethylformamide / 5 h / Ambient temperature
With
potassium carbonate;
In
N,N-dimethyl-formamide;
DOI:10.1021/jm00392a020
