2-Bromo-7-(4-fluoro-phenyl)-benzothiazole

Base Information Edit

Chemical Name:2-Bromo-7-(4-fluoro-phenyl)-benzothiazole
CAS No.:882055-21-2
Molecular Formula:C₁₃H₇BrFNS
Molecular Weight:308.174
Hs Code.:
Mol file:882055-21-2.mol

Synonyms:2-Bromo-7-(4-fluoro-phenyl)-benzothiazole

Suppliers and Price of 2-Bromo-7-(4-fluoro-phenyl)-benzothiazole

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
2-Bromo-7-(4-fluorophenyl)benzo[d]thiazole 95+%
1g
$ 698.00

Chemenu
2-bromo-7-(4-fluorophenyl)benzo[d]thiazole 95%
1g
$ 660.00

Alichem
2-Bromo-7-(4-fluorophenyl)benzo[d]thiazole
1g
$ 624.80

Total 2 raw suppliers

Chemical Property of 2-Bromo-7-(4-fluoro-phenyl)-benzothiazole Edit

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

2-Bromo-7-(4-fluorophenyl)benzo[d]thiazole 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-Bromo-7-(4-fluoro-phenyl)-benzothiazole

There total 4 articles about 2-Bromo-7-(4-fluoro-phenyl)-benzothiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 39.0%

: 882055-19-8
7-(4-fluoro-phenyl)-benzothiazole

: 882055-21-2
2-Bromo-7-(4-fluoro-phenyl)-benzothiazole

Guidance literature:: With n-butyllithium; carbon tetrabromide;
DOI:10.1016/j.bmcl.2012.07.068

Reference yield:

: 769-20-0
6-amino-7-bromo-1,3-benzothiazole

: 882055-21-2
2-Bromo-7-(4-fluoro-phenyl)-benzothiazole

Guidance literature:: Multi-step reaction with 3 steps

1: sodium nitrite; sulfuric acid; hypophosphorous acid

2: [1,1'-bis(diphenylphosphino)ferrocene]dichloropalladium(II); sodium carbonate / water; toluene; ethanol

3: n-butyllithium; carbon tetrabromide

With n-butyllithium; [1,1'-bis(diphenylphosphino)ferrocene]dichloropalladium(II); carbon tetrabromide; sulfuric acid; hypophosphorous acid; sodium carbonate; sodium nitrite; In ethanol; water; toluene; 1: |Sandmeyer Reaction / 2: |Suzuki-Miyaura Coupling;
DOI:10.1016/j.bmcl.2012.07.068

Reference yield:

: 533-30-2
1,3-benzothiazol-6-amine

: 882055-21-2
2-Bromo-7-(4-fluoro-phenyl)-benzothiazole

Guidance literature:: Multi-step reaction with 4 steps

1: bromine; acetic acid

2: sodium nitrite; sulfuric acid; hypophosphorous acid

3: [1,1'-bis(diphenylphosphino)ferrocene]dichloropalladium(II); sodium carbonate / water; toluene; ethanol

4: n-butyllithium; carbon tetrabromide

With n-butyllithium; [1,1'-bis(diphenylphosphino)ferrocene]dichloropalladium(II); carbon tetrabromide; sulfuric acid; bromine; hypophosphorous acid; sodium carbonate; acetic acid; sodium nitrite; In ethanol; water; toluene; 2: |Sandmeyer Reaction / 3: |Suzuki-Miyaura Coupling;
DOI:10.1016/j.bmcl.2012.07.068