Technology Process of (Z)-3-ethoxy-3-oxo-1-phenylprop-1-en-1-amine hydrochloride
There total 1 articles about (Z)-3-ethoxy-3-oxo-1-phenylprop-1-en-1-amine hydrochloride which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
ethyl 3-oxo-3-phenylpropionate;
With
ammonium acetate;
In
methanol;
for 12h;
Inert atmosphere;
Reflux;
With
hydrogenchloride;
In
diethyl ether; tert-butyl methyl ether;
for 0.5h;
Inert atmosphere;
DOI:10.1021/ja105674y
- Guidance literature:
-
With
bis(1,5-cyclooctadiene)diiridium(I) dichloride; 1,1'-bis[(S)-4,5-dihydro-3H-binaphtho[2,1-c:1',2'-e]phosphino]ferrocene; hydrogen;
In
methanol; dichloromethane;
at 20 ℃;
for 12h;
under 38002.6 Torr;
optical yield given as %ee;
enantioselective reaction;
DOI:10.1021/ja105674y