C₄₉H₆₈O₇SSi₂

Base Information

• Chemical Name: C₄₉H₆₈O₇SSi₂
• CAS No.: 1450629-21-6
• Molecular Formula: C₄₉H₆₈O₇SSi₂
• Molecular Weight: 857.312
• Mol file: 1450629-21-6.mol

Synonyms:C₄₉H₆₈O₇SSi₂

Chemical Property of C₄₉H₆₈O₇SSi₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₄₉H₆₈O₇SSi₂

There total 8 articles about C₄₉H₆₈O₇SSi₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

C42H46O4SSi + C17H36O3S2Si (1450629-05-6) → C49H68O7SSi2 (1450629-21-6)

Guidance literature:

C₄₂H₄₆O₄SSi; With lithium 4,4′-di(tert-butyl)biphenyl; In tetrahydrofuran; at -78 ℃; for 0.5h; Inert atmosphere;

C₁₇H₃₆O₃S₂Si; In tetrahydrofuran; at -78 ℃; for 0.5h; stereoselective reaction; Inert atmosphere;

DOI:10.1002/anie.201301682

Reference yield:

methyl 2,6-dideoxy-α-L-lyxo-hexopyranoside (4092-45-9,13322-79-7,17676-16-3,17676-19-6,19131-10-3,19131-11-4,33985-35-2,40878-56-6,53293-94-0,56733-47-2,62346-15-0,71305-70-9,72204-04-7,77210-24-3,78853-88-0,92007-64-2,133814-52-5,139756-72-2) → C49H68O7SSi2 (1450629-21-6)

Guidance literature:

Multi-step reaction with 7 steps

1.1: triethylamine / N,N-dimethyl-formamide / 1 h / 20 °C / Inert atmosphere

2.1: pyridine / dichloromethane / 0.5 h / 0 °C / Inert atmosphere

3.1: tetrahydrofuran / 20 °C / Inert atmosphere

4.1: lithium aluminium tetrahydride / diethyl ether / 1 h / -30 - 20 °C / Inert atmosphere

5.1: triethylamine / dichloromethane / 0 - 20 °C / Inert atmosphere

6.1: 1H-imidazole / N,N-dimethyl-formamide / 1 h / 20 °C / Inert atmosphere

7.1: lithium 4,4′-di(tert-butyl)biphenyl / tetrahydrofuran / 0.5 h / -78 °C / Inert atmosphere

7.2: 0.5 h / -78 °C / Inert atmosphere

With pyridine; 1H-imidazole; lithium aluminium tetrahydride; lithium 4,4′-di(tert-butyl)biphenyl; triethylamine; In tetrahydrofuran; diethyl ether; dichloromethane; N,N-dimethyl-formamide;

DOI:10.1002/anie.201301682

Reference yield:

C15H30O4SSi (1450629-02-3) → C49H68O7SSi2 (1450629-21-6)

Guidance literature:

Multi-step reaction with 4 steps

1.1: lithium aluminium tetrahydride / diethyl ether / 1 h / -30 - 20 °C / Inert atmosphere

2.1: triethylamine / dichloromethane / 0 - 20 °C / Inert atmosphere

3.1: 1H-imidazole / N,N-dimethyl-formamide / 1 h / 20 °C / Inert atmosphere

4.1: lithium 4,4′-di(tert-butyl)biphenyl / tetrahydrofuran / 0.5 h / -78 °C / Inert atmosphere

4.2: 0.5 h / -78 °C / Inert atmosphere

With 1H-imidazole; lithium aluminium tetrahydride; lithium 4,4′-di(tert-butyl)biphenyl; triethylamine; In tetrahydrofuran; diethyl ether; dichloromethane; N,N-dimethyl-formamide;

DOI:10.1002/anie.201301682

upstream raw materials:

C₁₇H₃₆O₃S₂Si

L-fucal

methyl 2,6-dideoxy-α-L-lyxo-hexopyranoside

C₁₃H₂₈O₄Si

Refernces