N4,N4-Diethyl-6-fluoro-2,4-pyrimidinediamine

Base Information

• Chemical Name: N4,N4-Diethyl-6-fluoro-2,4-pyrimidinediamine
• CAS No.: 165258-72-0
• Molecular Formula: C₈H₁₃FN₄
• Molecular Weight: 184.216
• Hs Code.: 2933599090
• DSSTox Substance ID: DTXSID50570586
• Wikidata: Q82458088
• Mol file: 165258-72-0.mol

Synonyms:165258-72-0;N4,N4-Diethyl-6-fluoro-2,4-pyrimidinediamine;4-N,4-N-diethyl-6-fluoropyrimidine-2,4-diamine;N4,N4-diethyl-6-fluoropyrimidine-2,4-diamine;N~4~,N~4~-Diethyl-6-fluoropyrimidine-2,4-diamine;DTXSID50570586;AKOS006273396

Chemical Property of N4,N4-Diethyl-6-fluoro-2,4-pyrimidinediamine

Chemical Property:

• Vapor Pressure: 3.64E-05mmHg at 25°C
• Refractive Index: 1.568
• Boiling Point: 353.2 °C at 760 mmHg
• Flash Point: 167.4 °C
• PSA: 55.04000
• Density: 1.201 g/cm³
• LogP: 1.62530
• XLogP3: 1.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 3
• Exact Mass: 184.11242459
• Heavy Atom Count: 13
• Complexity: 151

Purity/Quality:

99% ^*data from raw suppliers

2-AMINO-4-DIETHYLAMINO-6-FLUOROPYRIMIDINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCN(CC)C1=CC(=NC(=N1)N)F

Technology Process of N4,N4-Diethyl-6-fluoro-2,4-pyrimidinediamine

There total 1 articles about N4,N4-Diethyl-6-fluoro-2,4-pyrimidinediamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

2-amino-4,6-difluoropyrimidine (675-11-6) + diethylamine (109-89-7) → 2-amino-4-diethylamino-6-fluoropyrimidine (165258-72-0)

Guidance literature:

In N,N-dimethyl-formamide; at 50 - 60 ℃;

upstream raw materials:

2-amino-4,6-difluoropyrimidine

diethylamine

Refernces