1-[[5-(2,3-dihydro-1H-inden-5-yloxymethyl)furan-2-carbonyl]amino]-3-(3-morpholin-4-ylpropyl)thiourea

Base Information

• Chemical Name: 1-[[5-(2,3-dihydro-1H-inden-5-yloxymethyl)furan-2-carbonyl]amino]-3-(3-morpholin-4-ylpropyl)thiourea
• CAS No.: 7167-16-0
• Molecular Formula: C₉H₁₇NO₂S
• Molecular Weight: 203.305
• DSSTox Substance ID: DTXSID40413493
• Mol file: 7167-16-0.mol

Synonyms:7167-16-0;1-[[5-(2,3-dihydro-1H-inden-5-yloxymethyl)furan-2-carbonyl]amino]-3-(3-morpholin-4-ylpropyl)thiourea;DTXSID40413493;AKOS005370935

Chemical Property of 1-[[5-(2,3-dihydro-1H-inden-5-yloxymethyl)furan-2-carbonyl]amino]-3-(3-morpholin-4-ylpropyl)thiourea

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Density: 1.262g/cm³
• XLogP3: 2.9
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 8
• Exact Mass: 458.19877662
• Heavy Atom Count: 32
• Complexity: 619

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CC2=C(C1)C=C(C=C2)OCC3=CC=C(O3)C(=O)NNC(=S)NCCCN4CCOCC4

Technology Process of 1-[[5-(2,3-dihydro-1H-inden-5-yloxymethyl)furan-2-carbonyl]amino]-3-(3-morpholin-4-ylpropyl)thiourea

There total 6 articles about 1-[[5-(2,3-dihydro-1H-inden-5-yloxymethyl)furan-2-carbonyl]amino]-3-(3-morpholin-4-ylpropyl)thiourea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

cyclopenta-1,3-diene (542-92-7,25568-84-7,7313-32-8) → Bicyclo<2.2.1>heptan-2-sulfonsaeure-dimethylamid (7167-16-0)

Guidance literature:

Multi-step reaction with 3 steps

1: diethyl ether

2: H₂ / Pd-C / ethyl acetate

3: 120 °C

With hydrogen; palladium on activated charcoal; In diethyl ether; ethyl acetate;

DOI:10.1002/hlca.19620450633

Reference yield:

Δ5-Bicyclo<2.2.1>hepten-2-sulfonsaeuredimethylamid (7167-06-8) → Bicyclo<2.2.1>heptan-2-sulfonsaeure-dimethylamid (7167-16-0)

Guidance literature:

With hydrogen; palladium on activated charcoal; In methanol;

DOI:10.1002/hlca.19620450633

Reference yield:

Δ5-Bicyclo<2.2.1>hepten-2-sulfonsaeurefluorid (endo) → Bicyclo<2.2.1>heptan-2-sulfonsaeure-dimethylamid (7167-16-0)

Guidance literature:

Multi-step reaction with 2 steps

1: H₂ / Pd-C / ethyl acetate

2: 120 °C

With hydrogen; palladium on activated charcoal; In ethyl acetate;

DOI:10.1002/hlca.19620450633

upstream raw materials:

Δ⁵-Bicyclo<2.2.1>hepten-2-sulfonsaeuredimethylamid

dimethyl amine

cyclopenta-1,3-diene