(R)-N-Benzyl-1-(1-naphthyl)ethylamine hydrochloride

Base Information

• Chemical Name: (R)-N-Benzyl-1-(1-naphthyl)ethylamine hydrochloride
• CAS No.: 163831-65-0
• Molecular Formula: C19H19 N . Cl H
• Molecular Weight: 297.827
• Hs Code.: 2921499090
• European Community (EC) Number: 622-555-3
• Mol file: 163831-65-0.mol

Synonyms:946007-44-9;N-Benzyl-1-(naphthalen-1-yl)ethan-1-amine hydrochloride;N-benzyl-1-(1-naphthyl)ethylamine hydrochloride;SCHEMBL607723;BENZYL[(1S)-1-(NAPHTHALEN-1-YL)ETHYL]AMINE HYDROCHLORIDE;(R)-N-Benzyl-1-(1-naphthyl)ethylamine hydrochloride;AKOS024386607;SB82563;SB82595;DB-064517;benzyl[1-(naphthalen-1-yl)ethyl]amine hydrochloride;(S)-(-)-N-benzyl-1-(1-naphthyl)ethylamine hydrochloride

Chemical Property of (R)-N-Benzyl-1-(1-naphthyl)ethylamine hydrochloride

Chemical Property:

• Vapor Pressure: 8.06E-08mmHg at 25°C
• Melting Point: 259-261 °C(lit.)
• Boiling Point: 430.6°Cat760mmHg
• Flash Point: 214.2°C
• PSA: 12.03000
• Density: g/cm³
• LogP: 5.88350
• Storage Temp.: Inert atmosphere,Room Temperature
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 4
• Exact Mass: 297.1284273
• Heavy Atom Count: 21
• Complexity: 282

Purity/Quality:

98% ^*data from raw suppliers

(R)-N-Benzyl-1-(naphthalen-1-yl)ethanaminehydrochloride 95+% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C1=CC=CC2=CC=CC=C21)NCC3=CC=CC=C3.Cl

Technology Process of (R)-N-Benzyl-1-(1-naphthyl)ethylamine hydrochloride

There total 1 articles about (R)-N-Benzyl-1-(1-naphthyl)ethylamine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

(R)-<1-(1-Naphthyl)ethyl>ammonium chloride (82572-04-1) + sodium hydroxy(phenyl)methanesulfonate (4657-12-9) → benzyl-(1-naphthalen-1-yl-ethyl)-amine hydrochloride (163831-65-0)

Guidance literature:

(R)-<1-(1-Naphthyl)ethyl>ammonium chloride; sodium hydroxy(phenyl)methanesulfonate; With sodium cyanoborohydride; In methanol; at 20 ℃; for 20h;

With hydrogenchloride; In diethyl ether; at 0 ℃; for 13h;

DOI:10.1016/j.tetlet.2014.03.046

Reference yield:

benzyl-(1-naphthalen-1-yl-ethyl)-amine hydrochloride (163831-65-0) + N,N,N-trimethyl-3-oxo-3-(3-(trifluoromethyl)phenyl)propan-1-ammonium iodide (1224568-01-7) → (R)-3-(benzyl(1-(naphthalen-1-yl)ethyl)amino)-1-(3-(trifluoromethyl)phenyl)propan-1-one (1224568-03-9)

Guidance literature:

benzyl-(1-naphthalen-1-yl-ethyl)-amine hydrochloride; With sodium hydroxide; In water; toluene; at 20 ℃; for 0.5h;

N,N,N-trimethyl-3-oxo-3-(3-(trifluoromethyl)phenyl)propan-1-ammonium iodide; With potassium carbonate; In toluene; acetonitrile; at 80 ℃; for 14.33h;

upstream raw materials:

(R)-<1-(1-Naphthyl)ethyl>ammonium chloride

sodium hydroxy(phenyl)methanesulfonate

Downstream raw materials:

(R)-3-(benzyl(1-(naphthalen-1-yl)ethyl)amino)-1-(3-(trifluoromethyl)phenyl)propan-1-one

Refernces