C₃₀H₂₄N₆O₃

Base Information

• Chemical Name: C₃₀H₂₄N₆O₃
• CAS No.: 1428335-27-6
• Molecular Formula: C₃₀H₂₄N₆O₃
• Molecular Weight: 516.559
• Mol file: 1428335-27-6.mol

Synonyms:C₃₀H₂₄N₆O₃

Chemical Property of C₃₀H₂₄N₆O₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₀H₂₄N₆O₃

There total 6 articles about C₃₀H₂₄N₆O₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-b]pyridine (754214-56-7) + 6-bromo-N-(2-morpholino-5-phenylbenzo[d]oxazol-6-yl)picolinamide (1428335-99-2) → C30H24N6O3 (1428335-27-6)

Guidance literature:

With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; caesium carbonate; In 1,4-dioxane; water; at 100 - 120 ℃; for 2h; Sealed tube; Inert atmosphere;

Reference yield:

2-morpholino-6-nitro-5-phenylbenzo[d]oxazole (1428335-97-0) → C30H24N6O3 (1428335-27-6)

Guidance literature:

Multi-step reaction with 3 steps

1: iron; hydrogenchloride / ethanol; water / 2 h / 70 - 80 °C

2: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / N,N-dimethyl-formamide / 24 h / 20 - 30 °C

3: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; caesium carbonate / water; 1,4-dioxane / 2 h / 100 - 120 °C / Sealed tube; Inert atmosphere

With hydrogenchloride; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; iron; benzotriazol-1-ol; caesium carbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In 1,4-dioxane; ethanol; water; N,N-dimethyl-formamide;

Reference yield:

C17H17N3O2 (1428335-98-1) → C30H24N6O3 (1428335-27-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / N,N-dimethyl-formamide / 24 h / 20 - 30 °C

2: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; caesium carbonate / water; 1,4-dioxane / 2 h / 100 - 120 °C / Sealed tube; Inert atmosphere

With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; benzotriazol-1-ol; caesium carbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In 1,4-dioxane; water; N,N-dimethyl-formamide;

upstream raw materials:

2-morpholino-6-nitro-5-phenylbenzo[d]oxazole

C₁₇H₁₇N₃O₂

5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-b]pyridine

6-bromo-N-(2-morpholino-5-phenylbenzo[d]oxazol-6-yl)picolinamide

Refernces