(E)-N-benzylidene-2,4,6-trimethylaniline

Base Information

• Chemical Name: (E)-N-benzylidene-2,4,6-trimethylaniline
• CAS No.: 34143-89-0
• Molecular Formula: C₁₆H₁₇N
• Molecular Weight: 223.318
• Mol file: 34143-89-0.mol

Synonyms:(E)-N-benzylidene-2,4,6-trimethylaniline

Chemical Property of (E)-N-benzylidene-2,4,6-trimethylaniline

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-N-benzylidene-2,4,6-trimethylaniline

There total 18 articles about (E)-N-benzylidene-2,4,6-trimethylaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

2,4,6-trimethylaniline (88-05-1) + benzylamine (100-46-9) → 2,4,6-trimethyl-N-(phenylmethylene)benzenamine (34143-89-0,67080-14-2,17432-44-9)

Guidance literature:

With C₆₂H₇₂CuN₂O₆; oxygen; In acetonitrile; at 25 ℃; for 48h; under 25.8581 Torr;

DOI:10.1021/acscatal.9b02326

Reference yield: 94.0%

benzaldehyde (100-52-7) + 2,4,6-trimethylaniline (88-05-1) → (E)-N-benzylidene-2,4,6-trimethylaniline (34143-89-0)

Guidance literature:

In dichloromethane; at 20 ℃; for 2h; Inert atmosphere; Molecular sieve;

DOI:10.1002/chem.201703109

Reference yield: 92.0%

C15H24BNO2 + benzaldehyde (100-52-7) → 2,4,6-trimethyl-N-(phenylmethylene)benzenamine (34143-89-0,67080-14-2,17432-44-9)

Guidance literature:

In benzene-d6; at 25 ℃; for 1h; Inert atmosphere; Schlenk technique;

DOI:10.1002/anie.201814081

upstream raw materials:

benzaldehyde

2,4,6-trimethylaniline

dimesitylchlorogermane

2,4,6-trimethylaniline azide

Downstream raw materials:

(S)-2-cyclohexyl-2,3-dihydroquinazolin-4(1H)-one

(R)-2-phenyl-2,3-dihydroquinazolin-4(1H)-one

Refernces

• 1、 Junor, Glen P.,Romero, Erik A.,Chen, Xi,Jazzar, Rodolphe,Bertrand, Guy. "Readily Available Primary Aminoboranes as Powerful Reagents for Aldimine Synthesis". supporting information. p. 2875 - 2878. Retrieved 2019/02/13.
• 2、 Jangir, Ritambhara,Ansari, Mursaleem,Kaleeswaran, Dhananjayan,Rajaraman, Gopalan,Palaniandavar, Mallayan,Murugavel, Ramaswamy. "Unprecedented Copper(II) Complex with a Topoquinone-like Moiety as a Structural and Functional Mimic for Copper Amine Oxidase: Role of Copper(II) in the Genesis and Amine Oxidase Activity". . p. 10940 - 10950. Retrieved 2019/11/13.