8-aminooctanoic acid ethyl ester hydrochloride

Base Information

• Chemical Name: 8-aminooctanoic acid ethyl ester hydrochloride
• CAS No.: 29833-31-6
• Molecular Formula: C₁₀H₂₁NO₂*ClH
• Molecular Weight: 223.743
• Mol file: 29833-31-6.mol

Synonyms:8-aminooctanoic acid ethyl ester hydrochloride

Chemical Property of 8-aminooctanoic acid ethyl ester hydrochloride

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

ethyl8-aminooctanoateHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 8-aminooctanoic acid ethyl ester hydrochloride

There total 3 articles about 8-aminooctanoic acid ethyl ester hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

8-Aminooctanoic acid (1002-57-9) → 8-aminooctanoic acid ethyl ester hydrochloride (29833-31-6)

Guidance literature:

Reference yield: 95.0%

ethanol (64-17-5) + 8-Aminooctanoic acid (1002-57-9) → 8-aminooctanoic acid ethyl ester hydrochloride (29833-31-6)

Guidance literature:

With thionyl chloride; for 18h; Ambient temperature;

DOI:10.1021/jm00398a034

Reference yield:

2-azacyclononanone (935-30-8) + ethanol (64-17-5) → 8-aminooctanoic acid ethyl ester hydrochloride (29833-31-6)

Guidance literature:

With hydrogenchloride; thionyl chloride; Yield given. Multistep reaction; 1.) reflux, 8h;

DOI:10.1248/cpb.31.737

upstream raw materials:

2-azacyclononanone

ethanol

8-Aminooctanoic acid

Downstream raw materials:

35-amino-10,19,28-trioxo-9,18,27-triazapentatriacontanohydrazide dihydrobromide

ethyl 35-benzyloxycarbonylamino-10,19,28-trioxo-9,18,27-triazapentatriacontanoate

35-benzyloxycarbonylamino-10,19,28-trioxo-9,18,27-triazapentatriacontanohydrazide

Refernces

• 1、 Elsinghorst, Paul W.,González Tanarro, Camino M.,Gütschow, Michael. "Novel heterobivalent tacrine derivatives as cholinesterase inhibitors with notable selectivity toward butyrylcholinesterase". . p. 7540 - 7544. Retrieved 2007/10/03.
• 2、 Temple Jr.,Elliott,Montgomery. "Potential anticancer agents: 5-(N-substituted-aminocarbonyl)- and 5-(N-substituted-aminothiocarbonyl)-5,6,7,8-tetrahydrofolic acids". . p. 697 - 700. Retrieved 2007/10/02.