isobutyric acetic anhydride

Base Information

• Chemical Name: isobutyric acetic anhydride
• CAS No.: 7137-29-3
• Molecular Formula: C₆H₁₀O₃
• Molecular Weight: 130.144
• Mol file: 7137-29-3.mol

Synonyms:isobutyric acetic anhydride

Chemical Property of isobutyric acetic anhydride

Chemical Property:

Purity/Quality:

Safty Information:

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Technology Process of isobutyric acetic anhydride

There total 5 articles about isobutyric acetic anhydride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

acetyl chloride (75-36-5) + isobutyric Acid (79-31-2) → isobutyric acetic anhydride (7137-29-3)

Guidance literature:

With pyridine; In dichloromethane; Reflux;

DOI:10.1016/j.bmcl.2014.06.068

Reference yield:

thallium(I) 2-methylpropanoate (14332-14-0) + acetyl chloride (75-36-5) → isobutyric acetic anhydride (7137-29-3)

Guidance literature:

In diethyl ether;

DOI:10.1021/ja01011a040

Reference yield:

Ketene (463-51-4) + isobutyric Acid (79-31-2) → isobutyric acetic anhydride (7137-29-3)

Guidance literature:

DOI:10.1021/jo01038a017 DOI:10.1021/ja01620a060

upstream raw materials:

acetic anhydride

isobutyric Acid

Ketene

thallium(I) 2-methylpropanoate

Downstream raw materials:

geranyl 2-methylpropanoate

lantadene D

acetophenone

phenyl isopropyl ketone

Refernces

• 1、 Monika,Sharma, Ankesh,Suthar, Sharad Kumar,Aggarwal, Vaibhav,Lee, Hong Boon,Sharma, Manu. "Synthesis of lantadene analogs with marked in vitro inhibition of lung adenocarcinoma and TNF-α induced nuclear factor-kappa B (NF-κB) activation". supporting information. p. 3814 - 3818. Retrieved 2014/09/16.