O-(2-cloroacetilsaliciloil)-N-(2-acetilsaliciloil)-4-amminofenolo

Base Information

• Chemical Name: O-(2-cloroacetilsaliciloil)-N-(2-acetilsaliciloil)-4-amminofenolo
• CAS No.: 101974-27-0
• Molecular Formula: C₂₄H₁₈ClNO₇
• Molecular Weight: 467.862
• Mol file: 101974-27-0.mol

Synonyms:O-(2-cloroacetilsaliciloil)-N-(2-acetilsaliciloil)-4-amminofenolo

Chemical Property of O-(2-cloroacetilsaliciloil)-N-(2-acetilsaliciloil)-4-amminofenolo

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of O-(2-cloroacetilsaliciloil)-N-(2-acetilsaliciloil)-4-amminofenolo

There total 5 articles about O-(2-cloroacetilsaliciloil)-N-(2-acetilsaliciloil)-4-amminofenolo which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

O-(2-cloroacetilsaliciloil)-4-amminofenolo cloridrato + O-acetylsalicyloyl chloride (5538-51-2) → O-(2-cloroacetilsaliciloil)-N-(2-acetilsaliciloil)-4-amminofenolo (101974-27-0)

Guidance literature:

With pyridine; In 1,4-dioxane;

Reference yield:

4-nitro-phenol (100-02-7,78813-13-5,89830-32-0) → O-(2-cloroacetilsaliciloil)-N-(2-acetilsaliciloil)-4-amminofenolo (101974-27-0)

Guidance literature:

Multi-step reaction with 3 steps

1: 71 percent / pyridine / dioxane

2: 89 percent / H₂; 2.) HCl / 5percent Pd/C / ethyl acetate / 760 Torr / Ambient temperature

3: 86 percent / pyridine / dioxane

With pyridine; hydrogenchloride; hydrogen; palladium on activated charcoal; In 1,4-dioxane; ethyl acetate;

Reference yield:

acido 2-cloroacetilsalicilico (6090-79-5) → O-(2-cloroacetilsaliciloil)-N-(2-acetilsaliciloil)-4-amminofenolo (101974-27-0)

Guidance literature:

Multi-step reaction with 4 steps

1: thionyl chloride

2: 71 percent / pyridine / dioxane

3: 89 percent / H₂; 2.) HCl / 5percent Pd/C / ethyl acetate / 760 Torr / Ambient temperature

4: 86 percent / pyridine / dioxane

With pyridine; hydrogenchloride; thionyl chloride; hydrogen; palladium on activated charcoal; In 1,4-dioxane; ethyl acetate;

upstream raw materials:

O-acetylsalicyloyl chloride

4-nitro-phenol

acido 2-cloroacetilsalicilico

(chloroacetyl)salicylic acid chloride

Refernces