Cefadroxil anhydrous, L-

Base Information Edit

Chemical Name:Cefadroxil anhydrous, L-
CAS No.:144790-28-3
Molecular Formula:C₁₆H₁₇N₃O₅S
Molecular Weight:363.394
Hs Code.:2941901010
UNII:08N128E9PI
DSSTox Substance ID:DTXSID70162806
Nikkaji Number:J1.443.000H
Wikidata:Q27236413
ChEMBL ID:CHEMBL3039310
Mol file:144790-28-3.mol

Synonyms:L-Cefadroxil;144790-28-3;Cefadroxil anhydrous, L-;Cefadroxil, L-;Cefadroxil impurity D [EP];UNII-08N128E9PI;08N128E9PI;(6R,7R)-7-[[(2S)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;Cefadroxil monohydrate impurity D [EP];(6R,7R)-7-(((2S)-2-Amino-2-(4-hydroxyphenyl)acetyl)amino)-3-methyl-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid;(6R,7R)-7-[[2-amino-2-(4-hydroxyphenyl)acetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((2S)-amino(4-hydroxyphenyl)acetyl)amino)-3-methyl-8-oxo-, (6R,7R)-;(6R,7R)-7-((S)-2-Amino-2-(4-hydroxyphenyl)acetamido)-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-((amino(4-hydroxyphenyl)acetyl)amino)-3-methyl-8-oxo-, (6R-(6alpha,7beta(S*)))-;epi-Cefadroxil;Spectrum3_000329;BSPBio_001937;CHEMBL3039310;KBio3_001157;DTXSID70162806;NCGC00178903-01;CEFADROXIL IMPURITY D [EP IMPURITY];EN300-20142285;CEFADROXIL MONOHYDRATE IMPURITY D [EP IMPURITY];Q27236413;(6R,7R)-7-[(2S)-2-amino-2-(4-hydroxyphenyl)acetamido]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;5-THIA-1-AZABICYCLO(4.2.0)OCT-2-ENE-2-CARBOXYLIC ACID, 7-((AMINO(4-HYDROXYPHENYL)ACETYL)AMINO)-3-METHYL-8-OXO-, (6R-(6.ALPHA.,7.BETA.(S*)))-

Suppliers and Price of Cefadroxil anhydrous, L-

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
L-Cefadroxil
25mg
$ 1320.00

Sigma-Aldrich
Cefadroxil Related Compound D
25mg
$ 1160.00

Total 6 raw suppliers

Chemical Property of Cefadroxil anhydrous, L- Edit

Chemical Property:

Boiling Point:789.9±60.0 °C(Predicted)
PKA:3.12±0.50(Predicted)
PSA：161.75000
Density:1.59±0.1 g/cm3(Predicted)
LogP:1.62900
XLogP3:-2.1
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:4
Exact Mass:363.08889182
Heavy Atom Count:25
Complexity:629

Purity/Quality:

95% ^*data from raw suppliers

L-Cefadroxil ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(N2C(C(C2=O)NC(=O)C(C3=CC=C(C=C3)O)N)SC1)C(=O)O
Isomeric SMILES:CC1=C(N2[C@@H]([C@@H](C2=O)NC(=O)[C@H](C3=CC=C(C=C3)O)N)SC1)C(=O)O
Uses L-Cefadroxil (Cefadroxil EP Impurity D) is the stereoisomer of Cefadroxil (C235750), a semi-synthetic cephalosporin antibiotic. Antibacterial.

Technology Process of Cefadroxil anhydrous, L-

There total 13 articles about Cefadroxil anhydrous, L- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: cefadroxil/2,7-dihydroxynaphthalene complex

: 50370-12-2,144790-28-3
cefadroxil

Guidance literature:: With hydrogenchloride; In water; ethyl acetate; at 5 ℃; for 0.5h; pH=4;
DOI:10.1002/1099-0690(200105)2001:10<1817::AID-EJOC1817>3.0.CO;2-C