diazo-acetic acid 2-fluoro-phenyl ester

Base Information

• Chemical Name: diazo-acetic acid 2-fluoro-phenyl ester
• CAS No.: 274679-41-3
• Molecular Formula: C₈H₅FN₂O₂
• Molecular Weight: 180.138
• Mol file: 274679-41-3.mol

Synonyms:diazo-acetic acid 2-fluoro-phenyl ester

Chemical Property of diazo-acetic acid 2-fluoro-phenyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of diazo-acetic acid 2-fluoro-phenyl ester

There total 1 articles about diazo-acetic acid 2-fluoro-phenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

diazomethane (186581-53-3,908094-01-9,334-88-3) + 2-fluorophenyl chloroformate (70093-67-3) → diazo-acetic acid 2-fluoro-phenyl ester (274679-41-3)

Guidance literature:

In diethyl ether; at -5 - 0 ℃; for 3h;

Reference yield: 90.0%

triphenylphosphine (603-35-0) + diazo-acetic acid 2-fluoro-phenyl ester (274679-41-3) → C26H20FN2O2P

Guidance literature:

In diethyl ether; at -5 ℃; for 48h;

Reference yield: 76.0%

diazo-acetic acid 2-fluoro-phenyl ester (274679-41-3) → chloroacetic acid 4-nitrophenyl ester (777-84-4)

Guidance literature:

With hydrogenchloride; In chloroform; at 0 - 5 ℃;

upstream raw materials:

diazomethane

2-fluorophenyl chloroformate

Downstream raw materials:

chloroacetic acid 4-nitrophenyl ester

Refernces