C₂₇H₃₄O₃Se

Base Information

• Chemical Name: C₂₇H₃₄O₃Se
• CAS No.: 74137-05-6
• Molecular Formula: C₂₇H₃₄O₃Se
• Molecular Weight: 485.525
• Mol file: 74137-05-6.mol

Synonyms:C₂₇H₃₄O₃Se

Chemical Property of C₂₇H₃₄O₃Se

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₇H₃₄O₃Se

There total 2 articles about C₂₇H₃₄O₃Se which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3,3-(ethylenedioxy)-5-androsten-17β-ol (975-57-5) → C27H34O3Se (74137-05-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 90 percent / CrO₃*(pyridine)2 / CH₂Cl₂ / 12 h / Ambient temperature

2: 1.) diisopropylamine, n-BuLi / 1.) THF, -78 deg C, 15 min

With n-butyllithium; dipyridine chromium trioxide; diisopropylamine; In dichloromethane;

DOI:10.1021/jm00181a004

Reference yield:

Phenylselenyl chloride (5707-04-0) + 3,3-ethylenedioxy-5-androsten-17-one (3754-63-0) → C27H34O3Se (74137-04-5) + C27H34O3Se (74137-05-6)

Guidance literature:

With n-butyllithium; diisopropylamine; Yield given. Multistep reaction. Yields of byproduct given; 1.) THF, -78 deg C, 15 min;

DOI:10.1021/jm00181a004

Reference yield:

C27H34O3Se (74137-05-6) → testosterone (58-22-0)

Guidance literature:

Multi-step reaction with 3 steps

1: LiAlH₄ / diethyl ether / 2 h / -15 °C

2: p-toluenesulfonic acid / acetone / 2 h / Heating

3: 39 percent / triphenyltin hydride / toluene / 2 h / Heating

With lithium aluminium tetrahydride; triphenylstannane; toluene-4-sulfonic acid; In diethyl ether; acetone; toluene;

DOI:10.1021/jm00181a004

upstream raw materials:

Phenylselenyl chloride

3,3-ethylenedioxy-5-androsten-17-one

3,3-(ethylenedioxy)-5-androsten-17β-ol

Downstream raw materials:

testosterone

16alpha-(Phenylseleno)progesterone

Refernces