Technology Process of Pyridine, 2,3-dimethoxy-4-(1-methylethoxy)- (9CI)
There total 4 articles about Pyridine, 2,3-dimethoxy-4-(1-methylethoxy)- (9CI) which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 1.) PhLi, trimethyl borate, 2.) peracetic acid / 1.) THF, -40 deg C, 1 h; -70 deg C, 2 h
2: 77 percent / NaOMe / dimethylformamide / 1.5 h / Ambient temperature
3: 75 percent
4: 1.) n-BuLi, trimethylborate, 2.) peracetic acid / 1.) THF, 0 deg C, 1 h; -70 deg C, 2 h, 2.) aq. acetic acid, -70 deg C to r.t.
5: 93 percent / Ag2CO3 / hexane / 168 h / Ambient temperature
With
peracetic acid; n-butyllithium; Trimethyl borate; sodium methylate; phenyllithium; silver carbonate;
In
hexane; N,N-dimethyl-formamide;
DOI:10.1021/jo00100a017
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 75 percent
2: 1.) n-BuLi, trimethylborate, 2.) peracetic acid / 1.) THF, 0 deg C, 1 h; -70 deg C, 2 h, 2.) aq. acetic acid, -70 deg C to r.t.
3: 93 percent / Ag2CO3 / hexane / 168 h / Ambient temperature
With
peracetic acid; n-butyllithium; Trimethyl borate; silver carbonate;
In
hexane;
DOI:10.1021/jo00100a017
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 1.) n-BuLi, trimethylborate, 2.) peracetic acid / 1.) THF, 0 deg C, 1 h; -70 deg C, 2 h, 2.) aq. acetic acid, -70 deg C to r.t.
2: 93 percent / Ag2CO3 / hexane / 168 h / Ambient temperature
With
peracetic acid; n-butyllithium; Trimethyl borate; silver carbonate;
In
hexane;
DOI:10.1021/jo00100a017