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2-(2-((tert-Butoxycarbonyl)amino)ethoxy)acetic acid

Base Information Edit
  • Chemical Name:2-(2-((tert-Butoxycarbonyl)amino)ethoxy)acetic acid
  • CAS No.:142929-49-5
  • Molecular Formula:C9H17NO5
  • Molecular Weight:219.238
  • Hs Code.:2924199090
  • European Community (EC) Number:818-569-6
  • DSSTox Substance ID:DTXSID40566756
  • Wikidata:Q72448315
  • Mol file:142929-49-5.mol
2-(2-((tert-Butoxycarbonyl)amino)ethoxy)acetic acid

Synonyms:142929-49-5;2-(2-((tert-Butoxycarbonyl)amino)ethoxy)acetic acid;t-Boc-N-amido-PEG1-CH2CO2H;N-Boc-2-(2-aminoethoxy)acetic Acid;(2-Boc-Aminoethoxy)acetic acid;BocNH-PEG1-CH2COOH;Boc-NH-PEG1-CH2COOH;2-[2-[(2-methylpropan-2-yl)oxycarbonylamino]ethoxy]acetic acid;MFCD09909935;Acetic acid, [2-[[(1,1-dimethylethoxy)carbonyl]amino]ethoxy]-;2-(2-([(tert-Butoxy)carbonyl]amino)ethoxy)acetic acid;2-(2-{[(tert-butoxy)carbonyl]amino}ethoxy)acetic acid;{2-[(TERT-BUTOXYCARBONYL)AMINO]ETHOXY}ACETIC ACID;t-boc-N-amido-PEG1-acetic acid;Boc-5-Amino-3-oxapentanoic acid;(2-Boc-amino-ethoxy)-acetic acid;SCHEMBL320644;(2-Boc-amino-ethoxy)acetic acid;DTXSID40566756;t-Boc-N-Amido-PEG1-CH2COOH;UPBQMAHYLWJGDW-UHFFFAOYSA-N;N-Boc-(2-aminoethoxy)acetic acid;Acetic acid, 2-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethoxy]-;AKOS015908991;FS-5758;AC-26585;AM808137;BP-22041;SY033318;HY-140476;CS-0115466;5-tert.-butoxycarbonylamino-3-oxavaleric acid;EN300-74705;F52563;5-(t-butyloxycarbonyl-amino)-3-oxapentanoic acid;A807986;Z1171159734;2-[2-[(2-methylpropan-2-yl)oxycarbonylamino]ethoxy]ethanoic acid;2-[2-[[(2-methylpropan-2-yl)oxy-oxomethyl]amino]ethoxy]acetic acid;Aceticacid,[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethoxy]-(9CI)

Suppliers and Price of 2-(2-((tert-Butoxycarbonyl)amino)ethoxy)acetic acid
Supply Marketing:Edit
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • TRC
  • 2-(2-((tert-Butoxycarbonyl)amino)ethoxy)aceticAcid
  • 50mg
  • $ 60.00
  • SynQuest Laboratories
  • N-Boc-(2-aminoethoxy)acetic acid 97.0%
  • 5 g
  • $ 395.00
  • SynQuest Laboratories
  • N-Boc-(2-aminoethoxy)acetic acid 97.0%
  • 250 mg
  • $ 55.00
  • SynQuest Laboratories
  • N-Boc-(2-aminoethoxy)acetic acid 97.0%
  • 1 g
  • $ 125.00
  • purepeg
  • BocNH-PEG1-CH2COOH min.95%
  • 5 g
  • $ 248.00
  • Oakwood
  • (2-Boc-Aminoethoxy)acetic acid
  • 250mg
  • $ 30.00
  • Oakwood
  • (2-Boc-Aminoethoxy)acetic acid
  • 1g
  • $ 73.00
  • Oakwood
  • (2-Boc-Aminoethoxy)acetic acid
  • 5g
  • $ 285.00
  • Iris Biotech GmbH
  • Boc-O1Pen-OH*DCHA
  • 25 g
  • $ 1080.00
  • Iris Biotech GmbH
  • Boc-O1Pen-OH*DCHA
  • 5 g
  • $ 270.00
Total 34 raw suppliers
Chemical Property of 2-(2-((tert-Butoxycarbonyl)amino)ethoxy)acetic acid Edit
Chemical Property:
  • Vapor Pressure:3.3E-07mmHg at 25°C 
  • Refractive Index:1.462 
  • Boiling Point:391.2 °C at 760 mmHg 
  • PKA:3.44±0.10(Predicted) 
  • Flash Point:190.4 °C 
  • PSA:84.86000 
  • Density:1.151 g/cm3 
  • LogP:1.00320 
  • Storage Temp.:-20°C 
  • XLogP3:0.4
  • Hydrogen Bond Donor Count:2
  • Hydrogen Bond Acceptor Count:5
  • Rotatable Bond Count:7
  • Exact Mass:219.11067264
  • Heavy Atom Count:15
  • Complexity:221
Purity/Quality:

98%,99%, *data from raw suppliers

2-(2-((tert-Butoxycarbonyl)amino)ethoxy)aceticAcid *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:

SDS file from LookChem

Useful:
  • Canonical SMILES:CC(C)(C)OC(=O)NCCOCC(=O)O
  • Description t-Boc-N-amido-PEG1-CH2CO2H is a PEG linker containing a terminal carboxylic acid and Boc-protected amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.
  • Uses This is a crosslinker with a t-Boc protected amine on one end and a carboxyl group on the other end. The compound contains a single PEG unit to help improve solubility
Technology Process of 2-(2-((tert-Butoxycarbonyl)amino)ethoxy)acetic acid

There total 7 articles about 2-(2-((tert-Butoxycarbonyl)amino)ethoxy)acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With water; lithium hydroxide; In tetrahydrofuran; at 25 ℃; for 2h;
Guidance literature:
With lithium hydroxide; In tetrahydrofuran; at -10 ℃; for 3h;
DOI:10.1021/jm00094a002
Guidance literature:
With sodium hydride; In tetrahydrofuran; mineral oil; for 5h; Reflux;
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