deamino-[Arg⁸]-vasopressin

Base Information

• Chemical Name: deamino-[Arg⁸]-vasopressin
• CAS No.: 113-81-5
• Molecular Formula: C₄₆H₆₄N₁₄O₁₂S₂
• Molecular Weight: 1069.23
• Mol file: 113-81-5.mol

Synonyms:deamino-[Arg⁸]-vasopressin

Chemical Property of deamino-[Arg⁸]-vasopressin

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of deamino-[Arg⁸]-vasopressin

There total 5 articles about deamino-[Arg⁸]-vasopressin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(1-9)-NH2DDAVP → desmopressin (113-81-5,16679-58-6,120600-44-4,120600-45-5,135247-92-6,146556-44-7)

Guidance literature:

With iodine; acetic acid; In ethanol; water; at 26 ℃; for 18h; Inert atmosphere;

DOI:10.1021/acs.oprd.5b00103

Reference yield:

Mpa(Bzl)-Tyr(Bzl)-Phe-Gln-Asn-Cys(Bzl)-Pro-D-Arg(TOS)-Gly-NH2 (58928-35-1) → desmopressin (113-81-5,16679-58-6,120600-44-4,120600-45-5,135247-92-6,146556-44-7)

Guidance literature:

With ammonia; sodium; potassium hexacyanoferrate(III); Multistep reaction; 2) H₂O, pH= 6.7-7.0;

Reference yield:

C46H66N14O12S2 (6752-21-2) → deamino-[Arg8]-vasopressin (113-81-5)

Guidance literature:

With potassium hexacyanoferrate(III); In water; for 1h;

DOI:10.1135/cccc19810286

upstream raw materials:

Mpa(Bzl)-Tyr(Bzl)-Phe-Gln-Asn-Cys(Bzl)-Pro-D-Arg(TOS)-Gly-NH₂

C₄₆H₆₆N₁₄O₁₂S₂

Refernces

• 1、 -. "IMPROVED PROCESS FOR THE PREPARATION OF DESMOPRESSIN OR ITS PHARMACEUTICALLY ACCEPTABLE SALTS". . . Retrieved 2012/04/23.
• 2、 -. "Method and compositions for lipidization of hydrophilic molecules". . . Retrieved 2008/06/13.