Bromozinc(1+);propane

Base Information

• Chemical Name: Bromozinc(1+);propane
• CAS No.: 156567-57-6
• Molecular Formula: C3H7 Br Zn
• Molecular Weight: 188.383
• Hs Code.: 29319090
• DSSTox Substance ID: DTXSID10409363
• Mol file: 156567-57-6.mol

Synonyms:DTXSID10409363;J-009312

Chemical Property of Bromozinc(1+);propane

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: 1℉
• PSA: 0.00000
• Density: 0.947g/mLat25℃
• LogP: 2.20710
• Storage Temp.: 2-8°C
• Sensitive.: Air Sensitive
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 185.90225
• Heavy Atom Count: 5
• Complexity: 2

Purity/Quality:

98%,99%, ^*data from raw suppliers

Propylzinc bromide solution 0.5 M in THF ^*data from reagent suppliers

Safty Information:

• Hazard Codes: F,Xn
• Statements: 14-19-22-36/37/38-40-36/37-11
• Safety Statements: 16-26-33-36/37/39-43-45-36/37

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CC[CH2-].[Zn+]Br

Technology Process of Bromozinc(1+);propane

There total 3 articles about Bromozinc(1+);propane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

propyl bromide (106-94-5) + zinc (7440-66-6) → propylzinc bromide (156567-57-6)

Guidance literature:

zinc; With iodine; In N,N-dimethyl acetamide; at 20 ℃; for 0.166667h;

propyl bromide; In N,N-dimethyl acetamide; at 80 ℃; for 3h;

DOI:10.1021/jm301304e

Reference yield:

propyl bromide (106-94-5) → propylzinc bromide (156567-57-6)

Guidance literature:

With Zn#Cu; In further solvent(s); addn. of alkyl bromide in ethyl carbonate to Zn-Cu; heated to 95°C (3-4 h);

DOI:10.1016/0022-328X(89)87244-4

Reference yield:

zinc bromide + n-propylmagnesium bromide (927-77-5) → propylzinc bromide (156567-57-6)

Guidance literature:

In tetrahydrofuran; at 0 ℃; for 0.25h;

DOI:10.1021/acs.jmedchem.6b01668

upstream raw materials:

propyl bromide

zinc

n-propylmagnesium bromide

Downstream raw materials:

2-n-Propylbenzonitrile

2-(2-chlorophenyl)-7-(n-propyl)imidazo[4,5-c]quinolin-4(5H)-one

propiophenone

1-(p-tolyl)pentan-2-one

Refernces

• 1、 Prieri, Marion,Frita, Rosangela,Probst, Nicolas,Sournia-Saquet, Alix,Bourotte, Marilyne,Déprez, Benoit,Baulard, Alain R.,Willand, Nicolas. "Efficient analoging around ethionamide to explore thioamides bioactivation pathways triggered by boosters in Mycobacterium tuberculosis". . p. 35 - 46. Retrieved 2018/10/02.
• 2、 Kato, Atsushi,Hayashi, Erina,Miyauchi, Saori,Adachi, Isao,Imahori, Tatsushi,Natori, Yoshihiro,Yoshimura, Yuichi,Nash, Robert J.,Shimaoka, Hideyuki,Nakagome, Izumi,Koseki, Jun,Hirono, Shuichi,Takahata, Hiroki. "α-1-C-Butyl-1,4-Dideoxy-1,4-Imino-L-Arabinitol as a second-Generation iminosugar-based oral α-Glucosidase inhibitor for improving postprandial hyperglycemia". . p. 10347 - 10362. Retrieved 2013/02/23.