5-methyl-2-phenyl-2H-benzo[d][1,2,3]triazole

Base Information

• Chemical Name: 5-methyl-2-phenyl-2H-benzo[d][1,2,3]triazole
• CAS No.: 38610-46-7
• Molecular Formula: C₁₃H₁₁N₃
• Molecular Weight: 209.25
• Mol file: 38610-46-7.mol

Synonyms:5-methyl-2-phenyl-2H-benzo[d][1,2,3]triazole

Chemical Property of 5-methyl-2-phenyl-2H-benzo[d][1,2,3]triazole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of 5-methyl-2-phenyl-2H-benzo[d][1,2,3]triazole

There total 5 articles about 5-methyl-2-phenyl-2H-benzo[d][1,2,3]triazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

(E)-(2-bromo-4-methyl-phenyl)-phenyl-diazene (14336-14-2) → 5-methyl-2-phenyl-2H-benzo[d][1,2,3]triazole (38610-46-7)

Guidance literature:

With copper(l) iodide; sodium azide; N,N,N,N,-tetramethylethylenediamine; cetyltrimethylammonim bromide; In water; at 130 ℃; for 16h; Sealed tube; Inert atmosphere;

DOI:10.1002/chem.201303712

Reference yield: 55.0%

1-(4'-methyl-2'-nitrophenyl)-5-phenyltetrazole (122652-21-5) → 5-methyl-2-phenyl-2H-benzo[d][1,2,3]triazole (38610-46-7)

Guidance literature:

In various solvent(s); for 2h; Heating;

Reference yield:

trans-phenyl-p-tolyl-diazene (6720-39-4) → 2H-2-(4-methylphenyl)benzo[d]-1,2,3-triazole (3682-80-2) + 5-methyl-2-phenyl-2H-benzo[d][1,2,3]triazole (38610-46-7)

Guidance literature:

With dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; water; silver nitrate; silver(I) triflimide; In 1,2-dichloro-ethane; at 150 ℃; for 12h; Overall yield = 73 %; regioselective reaction; Schlenk technique;

DOI:10.1039/c6cc04341k

upstream raw materials:

1-(4'-methyl-2'-nitrophenyl)-5-phenyltetrazole

(E)-(2-bromo-4-methyl-phenyl)-phenyl-diazene

trans-phenyl-p-tolyl-diazene

Downstream raw materials:

5-(trans-2-dibenzofuran-3-yl-vinyl)-2-phenyl-2H-benzo[1,2,3]triazole

dimethyl 2-phenyl-2H-1,2,3-triazole-4,5-dicarboxylate

Refernces

• 1、 Shang, Xiaobo,Zhao, Shixian,Chen, Wanzhi,Chen, Chao,Qiu, Huayu. "Copper-catalyzed cascade cyclization reaction of 2-haloaryltriazenes and sodium azide: Selective synthesis of 2 H-benzotriazoles in water". supporting information. p. 1825 - 1828. Retrieved 2014/03/21.