Technology Process of 2-cyclohexyl-5,6,7,8-tetrahydroquinoline 1-oxide
There total 3 articles about 2-cyclohexyl-5,6,7,8-tetrahydroquinoline 1-oxide which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
Pd(OAc)2dppf; caesium carbonate;
In
toluene;
at 20 - 100 ℃;
for 12.01h;
regioselective reaction;
Inert atmosphere;
Schlenk technique;
DOI:10.1021/ja3113752
- Guidance literature:
-
With
tris(2,2-bipyridine)ruthenium(II) hexafluorophosphate; 1-acetoxy-1,2-benziodoxol-3-one; trifluoroacetic acid;
In
dichloromethane; water;
at 20 ℃;
for 24h;
Schlenk technique;
Inert atmosphere;
Irradiation;
DOI:10.1021/acs.joc.6b02891
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 3-chloro-benzenecarboperoxoic acid / chloroform / 12 h / 0 - 20 °C
2: tris(2,2-bipyridine)ruthenium(II) hexafluorophosphate; 1-acetoxy-1,2-benziodoxol-3-one; trifluoroacetic acid / water; dichloromethane / 24 h / 20 °C / Schlenk technique; Inert atmosphere; Irradiation
With
tris(2,2-bipyridine)ruthenium(II) hexafluorophosphate; 1-acetoxy-1,2-benziodoxol-3-one; 3-chloro-benzenecarboperoxoic acid; trifluoroacetic acid;
In
dichloromethane; chloroform; water;
DOI:10.1021/acs.joc.6b02891
