2-deoxy-D-ribonic acid

Base Information

• Chemical Name: 2-deoxy-D-ribonic acid
• CAS No.: 7284-15-3
• Molecular Formula: C₅H₁₀O₅
• Molecular Weight: 150.131
• Mol file: 7284-15-3.mol

Synonyms:2-deoxy-D-ribonic acid

Chemical Property of 2-deoxy-D-ribonic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-deoxy-D-ribonic acid

There total 15 articles about 2-deoxy-D-ribonic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(6-trans-p-coumaroyl)-3-O-β-D-glucopyranosyl-(5-acetyl)-2-deoxy-D-ribonic acid → 2-deoxy-D-ribonic acid (7284-15-3,29625-75-0) + D-glucose (50-99-7) + p-Coumaric Acid (7400-08-0,50940-26-6)

Guidance literature:

With hydrogenchloride; water; at 80 ℃; for 4h;

DOI:10.1016/j.foodchem.2014.03.097

Reference yield:

(6-trans-p-coumaroyl)-3-O-β-D-glucopyranosyl-2-deoxy-D-ribonic acid → 2-deoxy-D-ribonic acid (7284-15-3,29625-75-0) + D-glucose (50-99-7) + p-Coumaric Acid (7400-08-0,50940-26-6)

Guidance literature:

With hydrogenchloride; water; at 80 ℃; for 4h;

DOI:10.1016/j.foodchem.2014.03.097

Reference yield:

1,2:5,6-di-O-isopropylidene-α-D-glucofuranose (582-52-5) → 2-deoxy-D-ribonic acid (7284-15-3,29625-75-0) + 4,5,6-trihydroxy-2-oxohexanoic acid (17510-99-5)

Guidance literature:

Multi-step reaction with 5 steps

1.1: 1H-imidazole; sodium hydride / tetrahydrofuran / 1 h / 20 °C / Inert atmosphere

1.2: 2 h / Inert atmosphere

1.3: 1 h / Inert atmosphere

2.1: tri-n-butyl-tin hydride / toluene / Reflux

3.1: sulfuric acid / water / 1 h / Reflux

4.1: sodium hydroxide; oxygen; catalase / water / 5 h / 25 °C / pH 7.0 / Enzymatic reaction

5.1: sodium hydroxide; oxygen / water / 5 h / 130 °C / pH 8 / Sealed tube

With 1H-imidazole; sulfuric acid; oxygen; tri-n-butyl-tin hydride; sodium hydride; sodium hydroxide; catalase; In tetrahydrofuran; water; toluene;

DOI:10.1021/jf302959k

upstream raw materials:

2-Deoxy-D-ribose

D-glucose

O³-benzyl-D-glucose

3-deoxyglucosone

Downstream raw materials:

D-erythro-2-deoxy-pentonic acid-(N'-phenyl-hydrazide)

Refernces

• 1、 Milella, Luigi,Bader, Ammar,De Tommasi, Nunziatina,Russo, Daniela,Braca, Alessandra. "Antioxidant and free radical-scavenging activity of constituents from two Scorzonera species". . p. 298 - 304. Retrieved 2014/05/06.