6,7,8,9-TETRAHYDRO-5H-CYCLOHEPTA[B]PYRIDINE-N-OXIDE

Base Information

• Chemical Name: 6,7,8,9-TETRAHYDRO-5H-CYCLOHEPTA[B]PYRIDINE-N-OXIDE
• CAS No.: 41043-09-8
• Molecular Formula: C10H13 N O
• Molecular Weight: 163.219
• Hs Code.: 2933990090
• Mol file: 41043-09-8.mol

Synonyms:2,3-Cycloheptenopyridine-N-oxide;6,7,8,9-Tetrahydro-5H-cyclohepta[b]pyridine 1-oxide

Chemical Property of 6,7,8,9-TETRAHYDRO-5H-CYCLOHEPTA[B]PYRIDINE-N-OXIDE

Chemical Property:

• PSA: 25.46000
• LogP: 2.38400

Purity/Quality:

99.0%Min ^*data from raw suppliers

6,7,8,9-TETRAHYDRO-5H-CYCLOHEPTA[B]PYRIDINE-N-OXIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6,7,8,9-TETRAHYDRO-5H-CYCLOHEPTA[B]PYRIDINE-N-OXIDE

There total 5 articles about 6,7,8,9-TETRAHYDRO-5H-CYCLOHEPTA[B]PYRIDINE-N-OXIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

2,3-cycloheptenopyridine (7197-96-8) → 6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridine N-oxide (41043-09-8)

Guidance literature:

With dihydrogen peroxide; methyltrioxorhenium(VII); In dichloromethane; water; at 20 ℃; for 12h;

DOI:10.1002/anie.200601529

Reference yield:

2,3-cycloheptenopyridine (7197-96-8) → 6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridine N-oxide (41043-09-8) + 6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-9-ylamine (298181-76-7)

Guidance literature:

With dihydrogen peroxide; sodium carbonate; In chloroform; acetic acid;

Reference yield:

2,3-cycloheptenopyridine (7197-96-8) + sodium carbonate (497-19-8) → 6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridine N-oxide (41043-09-8)

Guidance literature:

2,3-cycloheptenopyridine; With dihydrogen peroxide; acetic acid; In water; at 70 ℃; for 12h; Inert atmosphere;

sodium carbonate; In chloroform; at 20 ℃; for 2h;

DOI:10.1039/c1ob06423a

upstream raw materials:

2,3-cycloheptenopyridine

sodium carbonate

cycloheptanone

Downstream raw materials:

(S)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-9-yl diphenylphosphinite

2-<(4-methoxy-6,7,8,9-tetrahydro-5H-cycloheptapyridin-9-yl)sulfinyl>-1H-benzimidazole

2-<(4-methoxy-6,7,8,9-tetrahydro-5H-cycloheptapyridin-9-yl)sulfinyl>-1H-benzimidazole

2,3-cycloheptenopyridine

Refernces

• 1、 Hardin Narayan, Alison R.,Sarpong, Richmond. "Indolizinones as synthetic scaffolds: Fundamental reactivity and the relay of stereochemical information". supporting information; experimental part. p. 70 - 78. Retrieved 2012/01/04.
• 2、 -. "TRICYCLIC COMPOUNDS AS GLUTAMATE RECEPTOR MODULATORS". Page/Page column 71. . Retrieved 2010/05/14.