Arginyllysine

Base Information

• Chemical Name: Arginyllysine
• CAS No.: 40968-46-5
• Molecular Formula: C₁₂H₂₆N₆O₃
• Molecular Weight: 302.377
• Hs Code.: 2925290090
• DSSTox Substance ID: DTXSID80423793
• Nikkaji Number: J1.390.552E
• Wikidata: Q27144132
• Metabolomics Workbench ID: 78687
• ChEMBL ID: CHEMBL380024
• Mol file: 40968-46-5.mol

Synonyms:Arg-Lys;arginine-lysine;arginyllysine

Chemical Property of Arginyllysine

Chemical Property:

• PSA: 217.64000
• LogP: 1.34870
• Storage Temp.: -15°C
• XLogP3: -4.7
• Hydrogen Bond Donor Count: 6
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 11
• Exact Mass: 302.20663871
• Heavy Atom Count: 21
• Complexity: 357

Purity/Quality:

99%+, ^*data from raw suppliers

ARG-LYS-OH ACETATE SALT 98.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(CCN)CC(C(=O)O)NC(=O)C(CCCN=C(N)N)N
• Isomeric SMILES: C(CCN)C[C@@H](C(=O)O)NC(=O)[C@H](CCCN=C(N)N)N

Technology Process of Arginyllysine

There total 6 articles about Arginyllysine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(S)-6-Benzyloxycarbonylamino-2-((S)-2-benzyloxycarbonylamino-5-guanidino-pentanoylamino)-hexanoic acid; hydrochloride → Arg-Lys (40968-46-5)

Guidance literature:

With hydrogen; acetic acid; palladium; In methanol;

DOI:10.1139/v60-262

Reference yield:

Cbo-nitro-L-Arg-ε-Cbo-L-Lys-benzylester (97615-54-8) → Arg-Lys (40968-46-5)

Guidance literature:

With hydrogen; palladium; In methanol; water; acetic acid;

Reference yield:

N-nitro-L-arginine (2149-70-4,13855-78-2,38733-00-5) → Arg-Lys (40968-46-5)

Guidance literature:

Multi-step reaction with 3 steps

1: aq. NaOH

2: (i) Et₃N, THF, DMF, (ii) /BRN= 2548552/, DCC

3: H₂ / Pd / methanol; acetic acid; H₂O

With sodium hydroxide; hydrogen; palladium; In methanol; water; acetic acid;

upstream raw materials:

Cbo-nitro-L-Arg-ε-Cbo-L-Lys-benzylester

N-nitro-L-arginine

N₅-[imino(nitroamino)methyl]-N₂-[(phenylmethoxy)carbonyl]-L-ornithine

L-arginine hydrochloride

Refernces