C₂₄H₂₇ClN₅O₆P

Base Information

• Chemical Name: C₂₄H₂₇ClN₅O₆P
• CAS No.: 1407520-52-8
• Molecular Formula: C₂₄H₂₇ClN₅O₆P
• Molecular Weight: 547.935
• Mol file: 1407520-52-8.mol

Synonyms:C₂₄H₂₇ClN₅O₆P

Chemical Property of C₂₄H₂₇ClN₅O₆P

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₄H₂₇ClN₅O₆P

There total 5 articles about C₂₄H₂₇ClN₅O₆P which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C12H16N2O5 (1407520-51-7) + (2-((2,5-dichloropyrimidin-4-yl)amino)phenyl)dimethyl phosphine oxide (1197953-49-3) → C24H27ClN5O6P (1407520-52-8)

Guidance literature:

With trifluoroacetic acid; In iso-butanol; at 100 ℃; for 18h;

Reference yield:

(3-methoxy-4-nitrophenyl)methanol (80866-88-2) → C24H27ClN5O6P (1407520-52-8)

Guidance literature:

Multi-step reaction with 5 steps

1: dipyridinium dichromate / dichloromethane / 2 h / 20 °C / molecular sieve

2: dichloromethane / 0.5 h / 20 °C

3: hydrogen / palladium 10% on activated carbon / methanol / 20 °C

4: sulfuric acid; guanidine nitrate / 3 h / 20 °C

5: trifluoroacetic acid / iso-butanol / 18 h / 100 °C

With dipyridinium dichromate; sulfuric acid; hydrogen; guanidine nitrate; trifluoroacetic acid; palladium 10% on activated carbon; In methanol; dichloromethane; iso-butanol;

Reference yield:

3-methoxy-4-nitrobenzaldehyde (80410-57-7) → C24H27ClN5O6P (1407520-52-8)

Guidance literature:

Multi-step reaction with 4 steps

1: dichloromethane / 0.5 h / 20 °C

2: hydrogen / palladium 10% on activated carbon / methanol / 20 °C

3: sulfuric acid; guanidine nitrate / 3 h / 20 °C

4: trifluoroacetic acid / iso-butanol / 18 h / 100 °C

With sulfuric acid; hydrogen; guanidine nitrate; trifluoroacetic acid; palladium 10% on activated carbon; In methanol; dichloromethane; iso-butanol;

upstream raw materials:

2-iodophenylamine

(3-methoxy-4-nitrophenyl)methanol

3-methoxy-4-nitrobenzaldehyde

ethyl 3-(3-methoxy-4-nitrophenyl)acrylate

Downstream raw materials:

C₂₂H₂₃ClN₅O₆P

Refernces