3-AMINO-4-PHENYLBUTAN-2-ONE HYDROCHLORIDE

Base Information

• Chemical Name: 3-AMINO-4-PHENYLBUTAN-2-ONE HYDROCHLORIDE
• CAS No.: 40513-35-7
• Molecular Formula: C10H13 N O
• Molecular Weight: 163.22
• Mol file: 40513-35-7.mol

Synonyms:2-butanone, 3-amino-4-phenyl-; 3-Amino-4-phenyl-2-butanone; 3-Amino-4-phenylbutan-2-one; PHENYLALANYLMETHANE

Chemical Property of 3-AMINO-4-PHENYLBUTAN-2-ONE HYDROCHLORIDE

Chemical Property:

• Vapor Pressure: 0.0114mmHg at 25°C
• Refractive Index: 1.533
• Boiling Point: 261.6°Cat760mmHg
• PKA: 7.14±0.33(Predicted)
• Flash Point: 112°C
• PSA: 43.09000
• Density: 1.043g/cm³
• LogP: 1.84570
• Storage Temp.: 2-8°C

Purity/Quality:

99%min ^*data from raw suppliers

3-Amino-4-phenylbutan-2-one 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-AMINO-4-PHENYLBUTAN-2-ONE HYDROCHLORIDE

There total 6 articles about 3-AMINO-4-PHENYLBUTAN-2-ONE HYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-acetylamino-4-phenyl-2-butanone (5463-26-3) → 3-amino-4-phenyl-butan-2-one (40513-35-7)

Guidance literature:

With hydrogenchloride;

Reference yield:

Phenylalanine (150-30-1,25191-15-5,658-69-5,67675-33-6) → 3-amino-4-phenyl-butan-2-one (40513-35-7)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine

2: diluted hydrochloric acid

With pyridine; hydrogenchloride;

Reference yield:

1-(N-tert.-butyloxycarbonyl-amino)-2-(S)-phenylethyl methyl ketone (860312-99-8) → 3-amino-4-phenyl-butan-2-one (40513-35-7)

Guidance literature:

With trifluoroacetic acid;

DOI:10.1016/S0960-894X(96)00559-8

upstream raw materials:

3-acetylamino-4-phenyl-2-butanone

1-(N-tert.-butyloxycarbonyl-amino)-2-(S)-phenylethyl methyl ketone

potassium ethoxide

Phenylalanine

Downstream raw materials:

(3,6-dimethylpyrazine-2,5-diyl)bis(phenylmethanone)

N-(1-benzyl-2-hydroxy-propyl)-benzamide

5-benzylidene-3-phenyl-4-methylpyrrolin-2-one

5-benzylidene-3-phenyl-4-methylpyrrolin-2-one

Refernces