DI-U-CHLOROBIS(5-HYDROXY-2-(1-(HYDROXYI&

Base Information

• Chemical Name: DI-U-CHLOROBIS(5-HYDROXY-2-(1-(HYDROXYI&
• CAS No.: 419581-64-9
• Molecular Formula: C16H16 Cl2 N2 O4 Pd2
• Molecular Weight: 584.058
• Mol file: 419581-64-9.mol

Synonyms:Bis[m-chloro[5-hydroxy-2-[1-(hydroxyimino)ethyl]phenyl]palladium]

Chemical Property of DI-U-CHLOROBIS(5-HYDROXY-2-(1-(HYDROXYI&

Chemical Property:

• Melting Point: 251-255 °C
• PSA: 105.64000
• LogP: 4.16020

Purity/Quality:

98%,99%, ^*data from raw suppliers

NajeraCatalystII ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Total 1 MSDS from other Authors

Useful:

• Uses: Najera Catalyst II (CAS# 419581-64-9) is an organometallic catalyst used for various cross-couplings reactions such as the Heck-Matsuda reaction of arenediazonium salts and the Suzuki-Miyaura cross-coupling reaction of aryl bromides. Najera Catalyst II has also been used in the catalytic rearrangement and dehydration of aldoximes.

Technology Process of DI-U-CHLOROBIS(5-HYDROXY-2-(1-(HYDROXYI&

There total 2 articles about DI-U-CHLOROBIS(5-HYDROXY-2-(1-(HYDROXYI& which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

lithium tetrachloropalladate + 4-hydroxyacetophenone oxime (34523-34-7) → (PdCl(N(OH)C(CH3)C6H3(OH)))2 (419581-64-9)

Guidance literature:

With sodium acetate; In methanol; to soln. of Li2PdCl4 in MeOH added soln. of oxime and AcONa in MeOH; soln. stirred for 2-3 ds at room temp.; H2O added; ppt. filtered off; elem. anal.;

DOI:10.1016/S0022-328X(02)01727-8

Reference yield: 75.0%

lithium tetrachloropalladate + 4-hydroxyacetophenone oxime (34523-34-7) + sodium acetate (127-09-3) → di‐μ‐chlorobis [5‐hydroxy‐2‐[1‐(hydroxyimino‐κN) ethyl] phenyl‐κC] palladium (II) (419581-64-9)

Guidance literature:

In methanol; C8H9NO2 (2 mmol) in MeOH and sodium acetate (2 mmol) added to Li2PdCl4 (2 mmol) in MeOH, stirred at room temp. for 72 h; filtered, pptd. with water added; elem. anal.;

DOI:10.1016/j.molcata.2004.11.030

upstream raw materials:

4-hydroxyacetophenone oxime

sodium acetate

Refernces

• 1、 Botella, Luis,Nájera, Carmen. "Cross-coupling reactions with boronic acids in water catalysed by oxime-derived palladacycles". . p. 46 - 57. Retrieved 2007/10/03.